3vwi: Difference between revisions

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 ==High resolution crystal structure of FraC in the monomeric form==
-<StructureSection load='3vwi' size='340' side='right' caption='[[3vwi]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
+<StructureSection load='3vwi' size='340' side='right'caption='[[3vwi]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3vwi]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Actfr Actfr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VWI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VWI FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3vwi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Actinia_fragacea Actinia fragacea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VWI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VWI FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3lim|3lim]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FraC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=396334 ACTFR])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vwi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vwi OCA], [https://pdbe.org/3vwi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vwi RCSB], [https://www.ebi.ac.uk/pdbsum/3vwi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vwi ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vwi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vwi OCA], [http://pdbe.org/3vwi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3vwi RCSB], [http://www.ebi.ac.uk/pdbsum/3vwi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3vwi ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/ACTPC_ACTFR ACTPC_ACTFR]] Pore-forming protein that forms cations-selective hydrophilic pores of around 1 nm and causes cardiac stimulation and hemolysis. Pore formation is a multi-step process that involves specific recognition of membrane sphingomyelin (but neither cholesterol nor phosphatidylcholine) using aromatic rich region and adjacent phosphocholine (POC) binding site, firm binding to the membrane (mainly driven by hydrophobic interactions) accompanied by the transfer of the N-terminal region to the lipid-water interface and finally pore formation after oligomerization of several monomers.<ref>PMID:19563820</ref>
+[https://www.uniprot.org/uniprot/ACTPC_ACTFR ACTPC_ACTFR] Pore-forming protein that forms cations-selective hydrophilic pores of around 1 nm and causes cardiac stimulation and hemolysis. Pore formation is a multi-step process that involves specific recognition of membrane sphingomyelin (but neither cholesterol nor phosphatidylcholine) using aromatic rich region and adjacent phosphocholine (POC) binding site, firm binding to the membrane (mainly driven by hydrophobic interactions) accompanied by the transfer of the N-terminal region to the lipid-water interface and finally pore formation after oligomerization of several monomers.<ref>PMID:19563820</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 20: / Line 19: @@
 </div>
 <div class="pdbe-citations 3vwi" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Cytolysin 3D structures|Cytolysin 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Actfr]]
+[[Category: Actinia fragacea]]
-[[Category: Caaveiro, J M.M]]
+[[Category: Large Structures]]
-[[Category: Gonzalez-Manas, J M]]
+[[Category: Caaveiro JMM]]
-[[Category: Morante, K]]
+[[Category: Gonzalez-Manas JM]]
-[[Category: Tanaka, K]]
+[[Category: Morante K]]
-[[Category: Tsumoto, K]]
+[[Category: Tanaka K]]
-[[Category: Actinoporin]]
+[[Category: Tsumoto K]]
-[[Category: Amphipathic alpha-helix]]
-[[Category: Beta-sandwich]]
-[[Category: Citolysin]]
-[[Category: Lipid raft]]
-[[Category: Membrane lipid]]
-[[Category: Pore-forming toxin]]
-[[Category: Secreted protein]]
-[[Category: Toxin]]