3vw7: Difference between revisions

<table><tr><td colspan='2'>[[3vw7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VW7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VW7 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=VPX:ETHYL+[(1R,3AR,4AR,6R,8AR,9S,9AS)-9-{(E)-2-[5-(3-FLUOROPHENYL)PYRIDIN-2-YL]ETHENYL}-1-METHYL-3-OXODODECAHYDRONAPHTHO[2,3-C]FURAN-6-YL]CARBAMATE'>VPX</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vw7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vw7 OCA], [https://pdbe.org/3vw7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vw7 RCSB], [https://www.ebi.ac.uk/pdbsum/3vw7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vw7 ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref> [https://www.uniprot.org/uniprot/PAR1_HUMAN PAR1_HUMAN] High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.<ref>PMID:10079109</ref>  

[[Category: Escherichia virus T4]]

[[Category: Homo sapiens]]

[[Category: Arlow DH]]

[[Category: Coughlin SR]]

[[Category: Dror RO]]

[[Category: Fung JJ]]

[[Category: Green HF]]

[[Category: Kobilka BK]]

[[Category: Palmer D]]

[[Category: Pandey A]]

[[Category: Shaw DE]]

[[Category: Srinivasan Y]]

[[Category: Weis WI]]

[[Category: Zhang C]]

[[Category: Zheng Y]]