3vtd: Difference between revisions

<StructureSection load='3vtd' size='340' side='right'caption='[[3vtd]], [[Resolution|resolution]] 2.70&Aring;' scene=''>

<table><tr><td colspan='2'>[[3vtd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VTD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VTD FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TKD:(1R,3R,7E,17BETA)-17-{(2R,6S)-6-HYDROXY-7-[(3S,5S,7S)-TRICYCLO[3.3.1.1~3,7~]DEC-1-YL]HEPT-4-YN-2-YL}-2-METHYLIDENE-9,10-SECOESTRA-5,7-DIENE-1,3-DIOL'>TKD</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vtd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vtd OCA], [https://pdbe.org/3vtd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vtd RCSB], [https://www.ebi.ac.uk/pdbsum/3vtd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vtd ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/VDR_RAT VDR_RAT] Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.<ref>PMID:17227670</ref>  

[[Category: Large Structures]]

[[Category: Rattus norvegicus]]

[[Category: Ikura T]]

[[Category: Ito N]]

[[Category: Kudo T]]

[[Category: Makishima M]]

[[Category: Nakabayashi M]]

[[Category: Tokiwa H]]

[[Category: Yamada S]]