5me5: Difference between revisions

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OCA

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 ==Crystal Structure of eiF4E from C. melo bound to a eIF4G peptide==
-<StructureSection load='5me5' size='340' side='right' caption='[[5me5]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
+<StructureSection load='5me5' size='340' side='right'caption='[[5me5]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[5me5]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ME5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ME5 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[5me5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cucumis_melo Cucumis melo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ME5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ME5 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5me5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5me5 OCA], [http://pdbe.org/5me5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5me5 RCSB], [http://www.ebi.ac.uk/pdbsum/5me5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5me5 ProSAT]</span></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5me5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5me5 OCA], [https://pdbe.org/5me5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5me5 RCSB], [https://www.ebi.ac.uk/pdbsum/5me5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5me5 ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/IF4E1_CUCME IF4E1_CUCME] Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome (PubMed:17026540, PubMed:28522457). Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures (PubMed:17026540, PubMed:28522457). Key component of recessive resistance to potyviruses and Tombusviridae genus Carmovirus such as melon necrotic spot virus (MNSV) (PubMed:17026540).<ref>PMID:17026540</ref> <ref>PMID:28522457</ref>   (Microbial infection) Susceptibility host factor required for viral infection by recruiting viral RNAs, including uncapped and non-polyadenylated RNA, to the host ribosomal complex via an interaction with viral genome-linked protein (VPg).<ref>PMID:17026540</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 16: / Line 19: @@
 </div>
 <div class="pdbe-citations 5me5" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Eukaryotic initiation factor 3D structures|Eukaryotic initiation factor 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Aranda-Regules, M]]
+[[Category: Cucumis melo]]
-[[Category: Miras, M]]
+[[Category: Large Structures]]
-[[Category: Querol-Audi, J]]
+[[Category: Aranda-Regules M]]
-[[Category: Silva, C]]
+[[Category: Miras M]]
-[[Category: Truniger, V]]
+[[Category: Querol-Audi J]]
-[[Category: Verdaguer, N]]
+[[Category: Silva C]]
-[[Category: Translation]]
+[[Category: Truniger V]]
-[[Category: Translation initiation eif4f complex]]
+[[Category: Verdaguer N]]