5ma2: Difference between revisions

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 ==PCE reductive dehalogenase from S. multivorans in complex with 4-iodophenol==
-<StructureSection load='5ma2' size='340' side='right' caption='[[5ma2]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
+<StructureSection load='5ma2' size='340' side='right'caption='[[5ma2]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[5ma2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfurospirillum_multivorans Sulfurospirillum multivorans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MA2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MA2 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[5ma2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfurospirillum_multivorans Sulfurospirillum multivorans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MA2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MA2 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BEN:BENZAMIDINE'>BEN</scene>, <scene name='pdbligand=BVQ:NORPSEUDO-B12'>BVQ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=IOL:4-IODOPHENOL'>IOL</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.879&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5m2g|5m2g]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEN:BENZAMIDINE'>BEN</scene>, <scene name='pdbligand=BVQ:NORPSEUDO-B12'>BVQ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=IOL:4-IODOPHENOL'>IOL</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ma2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ma2 OCA], [http://pdbe.org/5ma2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ma2 RCSB], [http://www.ebi.ac.uk/pdbsum/5ma2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ma2 ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ma2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ma2 OCA], [https://pdbe.org/5ma2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ma2 RCSB], [https://www.ebi.ac.uk/pdbsum/5ma2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ma2 ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/PCEA_SULMU PCEA_SULMU] Catalyzes the reductive dechlorination of tetrachloroethene (PCE) to trichloroethene (TCE) and of trichloroethene to cis-1,2-dichloroethene (DCE) (PubMed:8663199, PubMed:11976751, PubMed:12420164, PubMed:24433392, PubMed:28671181). In addition, trans-1,3-dichloropropene, 1,1,3-trichloropropene and 2,3-dichloropropene are reduced to a mixture of mono-chloropropenes, 1,1-dichloropropene, and 2-chloropropene, respectively (PubMed:11976751). Is also able to convert brominated phenols such as 4-bromophenol (4-BP), 2,4-dibromophenol (2,4-DBP) and 2,4,6-tribromophenol (2,4,6-TBP) (PubMed:28671181). Utilizes formate or pyruvate as electron donors (PubMed:16802174, PubMed:24433392). Titanium(III) citrate could also serve as electron donor (PubMed:11976751). Reduced methyl viologen can act as the artificial electron donor (PubMed:8663199, PubMed:11976751, PubMed:12420164).<ref>PMID:11976751</ref> <ref>PMID:12420164</ref> <ref>PMID:16802174</ref> <ref>PMID:24433392</ref> <ref>PMID:28671181</ref> <ref>PMID:8663199</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 17: / Line 19: @@
 </div>
 <div class="pdbe-citations 5ma2" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Dehalogenase 3D structures|Dehalogenase 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
+[[Category: Large Structures]]
 [[Category: Sulfurospirillum multivorans]]
-[[Category: Bommer, M]]
+[[Category: Bommer M]]
-[[Category: Diekert, G]]
+[[Category: Diekert G]]
-[[Category: Dobbek, H]]
+[[Category: Dobbek H]]
-[[Category: Hagen, W R]]
+[[Category: Hagen WR]]
-[[Category: Kunze, C]]
+[[Category: Kunze C]]
-[[Category: Schubert, T]]
+[[Category: Schubert T]]
-[[Category: Uksa, M]]
+[[Category: Uksa M]]
-[[Category: Organohalide respiration anaerobic crystallisation cobalamin]]
-[[Category: Oxidoreductase]]