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==Crystal structure (Type-1) of SAICAR synthetase from Pyrococcus horikoshii OT3==
==Crystal structure (Type-1) of SAICAR synthetase from Pyrococcus horikoshii OT3==
<StructureSection load='3u54' size='340' side='right' caption='[[3u54]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
<StructureSection load='3u54' size='340' side='right'caption='[[3u54]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3u54]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U54 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3U54 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3u54]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U54 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U54 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BU1:1,4-BUTANEDIOL'>BU1</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BU1:1,4-BUTANEDIOL'>BU1</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3u55|3u55]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u54 OCA], [https://pdbe.org/3u54 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u54 RCSB], [https://www.ebi.ac.uk/pdbsum/3u54 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u54 ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PH0239, purC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=70601 Pyrococcus horikoshii])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoribosylaminoimidazolesuccinocarboxamide_synthase Phosphoribosylaminoimidazolesuccinocarboxamide synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.6 6.3.2.6] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u54 OCA], [http://pdbe.org/3u54 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3u54 RCSB], [http://www.ebi.ac.uk/pdbsum/3u54 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3u54 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PUR7_PYRHO PUR7_PYRHO]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 3u54" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3u54" style="background-color:#fffaf0;"></div>
==See Also==
*[[SAICAR synthetase|SAICAR synthetase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Phosphoribosylaminoimidazolesuccinocarboxamide synthase]]
[[Category: Large Structures]]
[[Category: Pyrococcus horikoshii]]
[[Category: Pyrococcus horikoshii OT3]]
[[Category: Jeyakanthan, J]]
[[Category: Jeyakanthan J]]
[[Category: Kanagaraj, S]]
[[Category: Kanagaraj S]]
[[Category: Kanaujia, S P]]
[[Category: Kanaujia SP]]
[[Category: Manjunath, K]]
[[Category: Manjunath K]]
[[Category: Sekar, K]]
[[Category: Sekar K]]
[[Category: Atp-binding]]
[[Category: De novo purine biosynthesis]]
[[Category: Ligase]]
[[Category: Ligation of carboxy and amine group]]
[[Category: Phosphoribosylaminoimidazole-succinocarboxamide synthetase]]
[[Category: Purc]]
[[Category: Saicar synthetase-like fold]]

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