3u10: Difference between revisions

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OCA

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 <StructureSection load='3u10' size='340' side='right'caption='[[3u10]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3u10]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U10 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U10 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3u10]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U10 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U10 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CMP:ADENOSINE-3,5-CYCLIC-MONOPHOSPHATE'>CMP</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3u0z|3u0z]], [[3u11|3u11]], [[1q43|1q43]], [[3otf|3otf]]</div></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CMP:ADENOSINE-3,5-CYCLIC-MONOPHOSPHATE'>CMP</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HCN2, BCNG2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
 <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u10 OCA], [https://pdbe.org/3u10 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u10 RCSB], [https://www.ebi.ac.uk/pdbsum/3u10 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u10 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[https://www.uniprot.org/uniprot/HCN2_HUMAN HCN2_HUMAN]] Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). Can also transport ammonium in the distal nephron. Produces a large instantaneous current. Activated by cAMP. Modulated by intracellular chloride ions and pH; acidic pH shifts the activation to more negative voltages (By similarity).
+[https://www.uniprot.org/uniprot/HCN2_HUMAN HCN2_HUMAN] Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). Can also transport ammonium in the distal nephron. Produces a large instantaneous current. Activated by cAMP. Modulated by intracellular chloride ions and pH; acidic pH shifts the activation to more negative voltages (By similarity).
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 27: / Line 26: @@
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
 [[Category: Large Structures]]
-[[Category: Arrigoni, C]]
+[[Category: Arrigoni C]]
-[[Category: Bertinetti, D]]
+[[Category: Bertinetti D]]
-[[Category: Bertrand, J A]]
+[[Category: Bertrand JA]]
-[[Category: Bolognesi, M]]
+[[Category: Bolognesi M]]
-[[Category: Fasolini, M]]
+[[Category: Fasolini M]]
-[[Category: Gazzarrini, S]]
+[[Category: Gazzarrini S]]
-[[Category: Herberg, F W]]
+[[Category: Herberg FW]]
-[[Category: Lolicato, M]]
+[[Category: Lolicato M]]
-[[Category: Martin, H]]
+[[Category: Martin H]]
-[[Category: Moller, S]]
+[[Category: Moller S]]
-[[Category: Moroni, A]]
+[[Category: Moroni A]]
-[[Category: Nardini, M]]
+[[Category: Nardini M]]
-[[Category: Thiel, G]]
+[[Category: Thiel G]]
-[[Category: Transport protein]]