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==Corynebacterium glutamicum mycothiol/mycoredoxin1-dependent arsenate reductase Cg_ArsC2==
==Corynebacterium glutamicum mycothiol/mycoredoxin1-dependent arsenate reductase Cg_ArsC2==
<StructureSection load='3rh0' size='340' side='right' caption='[[3rh0]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
<StructureSection load='3rh0' size='340' side='right'caption='[[3rh0]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3rh0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Corynebacterium_glutamicum Corynebacterium glutamicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RH0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RH0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3rh0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Corynebacterium_glutamicum Corynebacterium glutamicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RH0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RH0 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.724&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3t38|3t38]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">arsX, Cgl0263, cg0319 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1718 Corynebacterium glutamicum])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rh0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rh0 OCA], [https://pdbe.org/3rh0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rh0 RCSB], [https://www.ebi.ac.uk/pdbsum/3rh0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rh0 ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Arsenate_reductase_(glutaredoxin) Arsenate reductase (glutaredoxin)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.20.4.1 1.20.4.1] </span></td></tr>
</table>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rh0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rh0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rh0 RCSB], [http://www.ebi.ac.uk/pdbsum/3rh0 PDBsum]</span></td></tr>
== Function ==
<table>
[https://www.uniprot.org/uniprot/ARSC2_CORGL ARSC2_CORGL] Involved in defense against toxic arsenate. Involved in the mycothiol/myoredoxin redox pathway which uses a mycothioltransferase mechanism; facilitates adduct formation between arsenate and mycothiol.<ref>PMID:19286650</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Corynebacterium glutamicum survives arsenic stress with arsenate reductases coupled to two distinct redox mechanisms.,Villadangos AF, Van Belle K, Wahni K, Tamu Dufe V, Freitas S, Nur H, De Galan S, Gil JA, Collet JF, Mateos LM, Messens J Mol Microbiol. 2011 Nov;82(4):998-1014. doi:, 10.1111/j.1365-2958.2011.07882.x. Epub 2011 Oct 27. PMID:22032722<ref>PMID:22032722</ref>
Corynebacterium glutamicum survives arsenic stress with arsenate reductases coupled to two distinct redox mechanisms.,Villadangos AF, Van Belle K, Wahni K, Tamu Dufe V, Freitas S, Nur H, De Galan S, Gil JA, Collet JF, Mateos LM, Messens J Mol Microbiol. 2011 Nov;82(4):998-1014. doi:, 10.1111/j.1365-2958.2011.07882.x. Epub 2011 Oct 27. PMID:22032722<ref>PMID:22032722</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3rh0" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Arsenate reductase|Arsenate reductase]]
*[[Arsenate reductase 3D structures|Arsenate reductase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Corynebacterium glutamicum]]
[[Category: Corynebacterium glutamicum]]
[[Category: Dufe, T V.]]
[[Category: Large Structures]]
[[Category: Messens, J.]]
[[Category: Dufe TV]]
[[Category: Wahni, K.]]
[[Category: Messens J]]
[[Category: Oxidoreductase]]
[[Category: Wahni K]]
[[Category: Reductase]]

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