3quh: Difference between revisions
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==Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Manganese(III)-porphyrin== | ==Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Manganese(III)-porphyrin== | ||
<StructureSection load='3quh' size='340' side='right' caption='[[3quh]], [[Resolution|resolution]] 2.70Å' scene=''> | <StructureSection load='3quh' size='340' side='right'caption='[[3quh]], [[Resolution|resolution]] 2.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3quh]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3quh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_Mu50 Staphylococcus aureus subsp. aureus Mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QUH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QUH FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | ||
<tr><td class="sblockLbl"><b>[[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MNR:PROTOPORPHYRIN+IX+CONTAINING+MN'>MNR</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3quh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3quh OCA], [https://pdbe.org/3quh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3quh RCSB], [https://www.ebi.ac.uk/pdbsum/3quh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3quh ProSAT]</span></td></tr> | |||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </table> | ||
<table> | == Function == | ||
[https://www.uniprot.org/uniprot/ISDH_STAAM ISDH_STAAM] Binds human plasma haptoglobin-hemoglobin complexes, haptoglobin and hemoglobin. Binds haptoglobin-hemoglobin complexes with significantly higher affinity than haptoglobin alone (By similarity). | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Molecular basis of recognition of antibacterial porphyrins by heme-transporter IsdH-NEAT3 of Staphylococcus aureus.,Moriwaki Y, Caaveiro JM, Tanaka Y, Tsutsumi H, Hamachi I, Tsumoto K Biochemistry. 2011 Aug 30;50(34):7311-20. Epub 2011 Aug 4. PMID:21797259<ref>PMID:21797259</ref> | Molecular basis of recognition of antibacterial porphyrins by heme-transporter IsdH-NEAT3 of Staphylococcus aureus.,Moriwaki Y, Caaveiro JM, Tanaka Y, Tsutsumi H, Hamachi I, Tsumoto K Biochemistry. 2011 Aug 30;50(34):7311-20. Epub 2011 Aug 4. PMID:21797259<ref>PMID:21797259</ref> | ||
From | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 3quh" style="background-color:#fffaf0;"></div> | |||
==See Also== | |||
*[[Haptoglobin receptor|Haptoglobin receptor]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Staphylococcus aureus subsp. aureus Mu50]] | ||
[[Category: | [[Category: Caaveiro JMM]] | ||
[[Category: | [[Category: Moriwaki Y]] | ||
[[Category: | [[Category: Tsumoto K]] | ||