3qbe: Difference between revisions

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<StructureSection load='3qbe' size='340' side='right'caption='[[3qbe]], [[Resolution|resolution]] 2.07&Aring;' scene=''>
<StructureSection load='3qbe' size='340' side='right'caption='[[3qbe]], [[Resolution|resolution]] 2.07&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3qbe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QBE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QBE FirstGlance]. <br>
<table><tr><td colspan='2'>[[3qbe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QBE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QBE FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.07&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3qbd|3qbd]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aroB, MRA_2566 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/3-dehydroquinate_synthase 3-dehydroquinate synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.4 4.2.3.4] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qbe OCA], [https://pdbe.org/3qbe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qbe RCSB], [https://www.ebi.ac.uk/pdbsum/3qbe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qbe ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qbe OCA], [https://pdbe.org/3qbe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qbe RCSB], [https://www.ebi.ac.uk/pdbsum/3qbe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qbe ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AROB_MYCTU AROB_MYCTU] Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).[HAMAP-Rule:MF_00110]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: 3-dehydroquinate synthase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Myctu]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Cheng, W C]]
[[Category: Cheng WC]]
[[Category: Wang, W C]]
[[Category: Wang WC]]
[[Category: Wen, Y H]]
[[Category: Wen YH]]
[[Category: Lyase]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Rossmann-fold]]
[[Category: Shikimate pathway]]

Latest revision as of 20:11, 1 November 2023

Crystal structure of the 3-Dehydroquinate Synthase (aroB) from Mycobacterium tuberculosisCrystal structure of the 3-Dehydroquinate Synthase (aroB) from Mycobacterium tuberculosis

Structural highlights

3qbe is a 1 chain structure with sequence from Mycobacterium tuberculosis H37Rv. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.07Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

AROB_MYCTU Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).[HAMAP-Rule:MF_00110]

3qbe, resolution 2.07Å

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OCA