3psn: Difference between revisions

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 ==Crystal structure of mouse VPS29 complexed with Mn2+==
-<StructureSection load='3psn' size='340' side='right' caption='[[3psn]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
+<StructureSection load='3psn' size='340' side='right'caption='[[3psn]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3psn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3lh7 3lh7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PSN FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3psn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3lh7 3lh7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PSN FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1w24|1w24]], [[1x2x|1x2x]], [[1z2w|1z2w]], [[2a22|2a22]], [[2r17|2r17]], [[3pso|3pso]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Vps29 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3psn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3psn OCA], [https://pdbe.org/3psn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3psn RCSB], [https://www.ebi.ac.uk/pdbsum/3psn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3psn ProSAT]</span></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoserine_phosphatase Phosphoserine phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.3 3.1.3.3] </span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3psn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3psn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3psn RCSB], [http://www.ebi.ac.uk/pdbsum/3psn PDBsum]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/VPS29_MOUSE VPS29_MOUSE] Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro).
+==See Also==
+*[[Vacuolar protein sorting-associated protein 3D structures|Vacuolar protein sorting-associated protein 3D structures]]
 __TOC__
 </StructureSection>
+[[Category: Large Structures]]
 [[Category: Mus musculus]]
-[[Category: Phosphoserine phosphatase]]
+[[Category: Chhabra S]]
-[[Category: Chhabra, S]]
+[[Category: Collins B]]
-[[Category: Collins, B]]
+[[Category: Ghai R]]
-[[Category: Ghai, R]]
+[[Category: Norwood S]]
-[[Category: Norwood, S]]
+[[Category: Shaw D]]
-[[Category: Shaw, D]]
+[[Category: Swarbrick J]]
-[[Category: Swarbrick, J]]
+[[Category: Valkov E]]
-[[Category: Valkov, E]]
-[[Category: Hydrolase]]
-[[Category: Membrane trafficking]]
-[[Category: Phosphtase fold]]
-[[Category: Scaffolding]]
-[[Category: Snx1]]
-[[Category: Tbc1d5]]
-[[Category: Vps35]]