3psn: Difference between revisions

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[[Image:3psn.jpg|left|200px]]


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==Crystal structure of mouse VPS29 complexed with Mn2+==
The line below this paragraph, containing "STRUCTURE_3psn", creates the "Structure Box" on the page.
<StructureSection load='3psn' size='340' side='right'caption='[[3psn]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3psn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3lh7 3lh7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PSN FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
{{STRUCTURE_3psn|  PDB=3psn  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3psn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3psn OCA], [https://pdbe.org/3psn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3psn RCSB], [https://www.ebi.ac.uk/pdbsum/3psn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3psn ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/VPS29_MOUSE VPS29_MOUSE] Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro).


===Crystal structure of mouse VPS29 complexed with Mn2+===
==See Also==
 
*[[Vacuolar protein sorting-associated protein 3D structures|Vacuolar protein sorting-associated protein 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
3PSN is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3lh7 3lh7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSN OCA].
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Phosphoserine phosphatase]]
[[Category: Chhabra S]]
[[Category: Chhabra, S.]]
[[Category: Collins B]]
[[Category: Collins, B.]]
[[Category: Ghai R]]
[[Category: Ghai, R.]]
[[Category: Norwood S]]
[[Category: Norwood, S.]]
[[Category: Shaw D]]
[[Category: Shaw, D.]]
[[Category: Swarbrick J]]
[[Category: Swarbrick, J.]]
[[Category: Valkov E]]
[[Category: Valkov, E.]]
[[Category: Hydrolase]]
[[Category: Membrane trafficking]]
[[Category: Phosphtase fold]]
[[Category: Scaffolding]]
[[Category: Snx1]]
[[Category: Tbc1d5]]
[[Category: Vps35]]
 
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