3our: Difference between revisions

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-[[Image:3our.jpg|left|200px]]
-<!--
+==Crystal structure of complex between EIIA and a novel pyruvate decarboxylase==
-The line below this paragraph, containing "STRUCTURE_3our", creates the "Structure Box" on the page.
+<StructureSection load='3our' size='340' side='right'caption='[[3our]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3our]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_vulnificus_CMCP6 Vibrio vulnificus CMCP6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OUR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OUR FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3our FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3our OCA], [https://pdbe.org/3our PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3our RCSB], [https://www.ebi.ac.uk/pdbsum/3our PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3our ProSAT]</span></td></tr>
-{{STRUCTURE_3our|  PDB=3our  |  SCENE=  }}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/FRSA_VIBVU FRSA_VIBVU] Catalyzes the hydrolysis of esters (PubMed:30951551). In vitro, prefers short chain alkanoate ester as substrate. Displays highest activity towards p-nitrophenyl acetate (pNPA). Has weaker activity towards p-nitrophenyl butyrate (pNPB) (PubMed:30951551).<ref>PMID:30951551</ref>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+The interaction between fermentation-respiration switch (FrsA) protein and glucose-specific enzyme IIA(Glc) increases glucose fermentation under oxygen-limited conditions. We show that FrsA converts pyruvate to acetaldehyde and carbon dioxide in a cofactor-independent manner and that its pyruvate decarboxylation activity is enhanced by the dephosphorylated form of IIA(Glc) (d-IIA(Glc)). Crystal structures of FrsA and its complex with d-IIA(Glc) revealed residues required for catalysis as well as the structural basis for the activation by d-IIA(Glc).
-===Crystal structure of complex between EIIA and a novel pyruvate decarboxylase===
+FrsA functions as a cofactor-independent decarboxylase to control metabolic flux.,Lee KJ, Jeong CS, An YJ, Lee HJ, Park SJ, Seok YJ, Kim P, Lee JH, Lee KH, Cha SS Nat Chem Biol. 2011 May 29. PMID:21623357<ref>PMID:21623357</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
+<div class="pdbe-citations 3our" style="background-color:#fffaf0;"></div>
-==About this Structure==
+==See Also==
-[[3our]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_vulnificus Vibrio vulnificus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OUR OCA].
+*[[Phosphotransferase 3D structures|Phosphotransferase 3D structures]]
-[[Category: Vibrio vulnificus]]
+*[[Pyruvate decarboxylase|Pyruvate decarboxylase]]
-[[Category: An, Y J.]]
+== References ==
-[[Category: Cha, S S.]]
+<references/>
-[[Category: Jeong, C S.]]
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Vibrio vulnificus CMCP6]]
+[[Category: An YJ]]
+[[Category: Cha SS]]
+[[Category: Jeong CS]]