3nr2: Difference between revisions

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 ==Crystal structure of Caspase-6 zymogen==
-<StructureSection load='3nr2' size='340' side='right' caption='[[3nr2]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
+<StructureSection load='3nr2' size='340' side='right'caption='[[3nr2]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3nr2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NR2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NR2 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3nr2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NR2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NR2 FirstGlance]. <br>
-</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3od5|3od5]]</td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Caspase-6 Caspase-6], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.59 3.4.22.59] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nr2 OCA], [https://pdbe.org/3nr2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nr2 RCSB], [https://www.ebi.ac.uk/pdbsum/3nr2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nr2 ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nr2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nr2 RCSB], [http://www.ebi.ac.uk/pdbsum/3nr2 PDBsum]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/CASP6_HUMAN CASP6_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 15: / Line 17: @@
 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 3nr2" style="background-color:#fffaf0;"></div>
 ==See Also==
-*[[Caspase|Caspase]]
+*[[Caspase 3D structures|Caspase 3D structures]]
 *[[Caspase-6 and neurodegeneration|Caspase-6 and neurodegeneration]]
 *[[Molecular Playground/Caspase-6 and neurodegeneration|Molecular Playground/Caspase-6 and neurodegeneration]]
@@ Line 25: / Line 28: @@
 __TOC__
 </StructureSection>
-[[Category: Caspase-6]]
 [[Category: Homo sapiens]]
-[[Category: Liu, X]]
+[[Category: Large Structures]]
-[[Category: Mi, W]]
+[[Category: Liu X]]
-[[Category: Su, X D]]
+[[Category: Mi W]]
-[[Category: Wang, K T]]
+[[Category: Su X-D]]
-[[Category: Wang, X J]]
+[[Category: Wang K-T]]
-[[Category: Caspase domain]]
+[[Category: Wang X-J]]
-[[Category: Cysteine protease]]
-[[Category: Hydrolase]]