3nl0: Difference between revisions

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 ==Mutant P44S M296I of Foot-and-mouth disease Virus RNA-dependent RNA polymerase==
-<StructureSection load='3nl0' size='340' side='right' caption='[[3nl0]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
+<StructureSection load='3nl0' size='340' side='right'caption='[[3nl0]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3nl0]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Aphthovirus_c Aphthovirus c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NL0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NL0 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3nl0]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Foot_and_mouth_disease_virus_C Foot and mouth disease virus C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NL0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NL0 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1wne|1wne]], [[1u09|1u09]], [[2e9r|2e9r]], [[2e9t|2e9t]], [[2e9z|2e9z]], [[2ec0|2ec0]], [[3nky|3nky]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">3D ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12116 Aphthovirus C])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nl0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nl0 OCA], [https://pdbe.org/3nl0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nl0 RCSB], [https://www.ebi.ac.uk/pdbsum/3nl0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nl0 ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nl0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nl0 OCA], [http://pdbe.org/3nl0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3nl0 RCSB], [http://www.ebi.ac.uk/pdbsum/3nl0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3nl0 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/Q9QCE4_9PICO Q9QCE4_9PICO]] Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266]  RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS000199_004_010047]
+[https://www.uniprot.org/uniprot/Q9QCE4_9PICO Q9QCE4_9PICO] Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266]  RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS000199_004_010047]
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 22: / Line 21: @@
 ==See Also==
-*[[RNA polymerase|RNA polymerase]]
+*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Aphthovirus c]]
+[[Category: Foot and mouth disease virus C]]
-[[Category: Agudo, R]]
+[[Category: Large Structures]]
-[[Category: Arias, A]]
+[[Category: Agudo R]]
-[[Category: Domingo, E]]
+[[Category: Arias A]]
-[[Category: Ferrer-Orta, C]]
+[[Category: Domingo E]]
-[[Category: Perez-Luque, R]]
+[[Category: Ferrer-Orta C]]
-[[Category: Verdaguer, N]]
+[[Category: Perez-Luque R]]
-[[Category: 3d polymerase]]
+[[Category: Verdaguer N]]
-[[Category: Foot-and-mouth disease virus picornavirus]]
-[[Category: Rna dependent rna polymerase]]
-[[Category: Transferase-rna complex]]