3mul: Difference between revisions

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-[[Image:3mul.png|left|200px]]
-<!--
+==Crystal structure of Brd4 bromodomain 1 with butyrylated histone H3-K(buty)14==
-The line below this paragraph, containing "STRUCTURE_3mul", creates the "Structure Box" on the page.
+<StructureSection load='3mul' size='340' side='right'caption='[[3mul]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3mul]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MUL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MUL FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTK:N~6~-BUTANOYL-L-LYSINE'>BTK</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-{{STRUCTURE_3mul|  PDB=3mul  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mul FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mul OCA], [https://pdbe.org/3mul PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mul RCSB], [https://www.ebi.ac.uk/pdbsum/3mul PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mul ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/BRD4_MOUSE BRD4_MOUSE] Plays a role in a process governing chromosomal dynamics during mitosis.<ref>PMID:10938129</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mu/3mul_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3mul ConSurf].
+<div style="clear:both"></div>
-===Crystal structure of Brd4 bromodomain 1 with butyrylated histone H3-K(buty)14===
+==See Also==
+*[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]]
+== References ==
-==About this Structure==
+<references/>
-[[3mul]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MUL OCA].
+__TOC__
+</StructureSection>
-==Reference==
+[[Category: Homo sapiens]]
-<ref group="xtra">PMID:20715035</ref><references group="xtra"/>
+[[Category: Large Structures]]
 [[Category: Mus musculus]]
-[[Category: Geyer, M.]]
+[[Category: Geyer M]]
-[[Category: Vollmuth, F.]]
+[[Category: Vollmuth F]]