3lt2: Difference between revisions

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==Enoyl-ACP Reductase from Plasmodium falciparum (PfENR) in complex with triclosan variant T3==
==Enoyl-ACP Reductase from Plasmodium falciparum (PfENR) in complex with triclosan variant T3==
<StructureSection load='3lt2' size='340' side='right' caption='[[3lt2]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='3lt2' size='340' side='right'caption='[[3lt2]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3lt2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plafa Plafa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LT2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LT2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3lt2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LT2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LT2 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FT3:2-(2,4-DICHLOROPHENOXY)-5-(HYDROXYMETHYL)PHENOL'>FT3</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1uh5|1uh5]], [[1v35|1v35]], [[2oos|2oos]], [[2ol4|2ol4]], [[1zxl|1zxl]], [[1zsn|1zsn]], [[3lsy|3lsy]], [[3lt0|3lt0]], [[3lt1|3lt1]], [[3lt4|3lt4]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FT3:2-(2,4-DICHLOROPHENOXY)-5-(HYDROXYMETHYL)PHENOL'>FT3</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fabI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 PLAFA])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lt2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lt2 OCA], [https://pdbe.org/3lt2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lt2 RCSB], [https://www.ebi.ac.uk/pdbsum/3lt2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lt2 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lt2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lt2 OCA], [http://pdbe.org/3lt2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3lt2 RCSB], [http://www.ebi.ac.uk/pdbsum/3lt2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3lt2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9BJJ9_PLAFA Q9BJJ9_PLAFA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Enoyl-Acyl-Carrier Protein Reductase|Enoyl-Acyl-Carrier Protein Reductase]]
*[[Enoyl-Acyl-Carrier Protein Reductase 3D structures|Enoyl-Acyl-Carrier Protein Reductase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Plafa]]
[[Category: Large Structures]]
[[Category: Bhargav, S P]]
[[Category: Plasmodium falciparum]]
[[Category: Maity, K]]
[[Category: Bhargav SP]]
[[Category: Suguna, K]]
[[Category: Maity K]]
[[Category: Surolia, A]]
[[Category: Suguna K]]
[[Category: Surolia, N]]
[[Category: Surolia A]]
[[Category: Enoyl-acp reductase]]
[[Category: Surolia N]]
[[Category: Oxidoreductase]]
[[Category: P falciparum]]
[[Category: Triclosan]]
[[Category: Triclosan variant]]

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