3log: Difference between revisions

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<StructureSection load='3log' size='340' side='right'caption='[[3log]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
<StructureSection load='3log' size='340' side='right'caption='[[3log]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3log]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LOG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LOG FirstGlance]. <br>
<table><tr><td colspan='2'>[[3log]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LOG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LOG FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.73&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mbtI, MT2454, Rv2386c ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3log FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3log OCA], [https://pdbe.org/3log PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3log RCSB], [https://www.ebi.ac.uk/pdbsum/3log PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3log ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3log FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3log OCA], [https://pdbe.org/3log PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3log RCSB], [https://www.ebi.ac.uk/pdbsum/3log PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3log ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/MBTI_MYCTU MBTI_MYCTU]] Mediates the production of salicylate from chorismate via an isochorismate intermediate. Presents both isochorismate synthase and isochorismate-pyruvate lyase activities. Salycilate is the starter unit in the production of the virulence-conferring salicylate-based siderophore mycobactin.<ref>PMID:16923875</ref>
[https://www.uniprot.org/uniprot/MBTI_MYCTU MBTI_MYCTU] Mediates the production of salicylate from chorismate via an isochorismate intermediate. Presents both isochorismate synthase and isochorismate-pyruvate lyase activities. Salycilate is the starter unit in the production of the virulence-conferring salicylate-based siderophore mycobactin.<ref>PMID:16923875</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Baker, E N]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Bulloch, E M.M]]
[[Category: Baker EN]]
[[Category: Johnston, J M]]
[[Category: Bulloch EMM]]
[[Category: Lott, J S]]
[[Category: Johnston JM]]
[[Category: Anthranilate]]
[[Category: Lott JS]]
[[Category: Chorismate]]
[[Category: Ion transport]]
[[Category: Isochorismate]]
[[Category: Isochorismate lyase]]
[[Category: Isochorismate synthase]]
[[Category: Isomerase]]
[[Category: Lyase]]
[[Category: Metal-binding]]
[[Category: Multifunctional enzyme]]
[[Category: Salicylate]]
[[Category: Transport]]

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