3hr8: Difference between revisions

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==Crystal Structure of Thermotoga maritima RecA==
==Crystal Structure of Thermotoga maritima RecA==
<StructureSection load='3hr8' size='340' side='right' caption='[[3hr8]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='3hr8' size='340' side='right'caption='[[3hr8]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3hr8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HR8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HR8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3hr8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HR8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HR8 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">recA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 ATCC 43589])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hr8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hr8 OCA], [http://pdbe.org/3hr8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hr8 RCSB], [http://www.ebi.ac.uk/pdbsum/3hr8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hr8 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hr8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hr8 OCA], [https://pdbe.org/3hr8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hr8 RCSB], [https://www.ebi.ac.uk/pdbsum/3hr8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hr8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RECA_THEMA RECA_THEMA]] Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.[HAMAP-Rule:MF_00268]  
[https://www.uniprot.org/uniprot/RECA_THEMA RECA_THEMA] Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.[HAMAP-Rule:MF_00268]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hr/3hr8_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hr/3hr8_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hr8 ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hr8 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
*[[3D structures of recombinase A|3D structures of recombinase A]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 43589]]
[[Category: Large Structures]]
[[Category: Ban, C]]
[[Category: Thermotoga maritima]]
[[Category: Heo, S D]]
[[Category: Ban C]]
[[Category: Jeon, W J]]
[[Category: Heo S-D]]
[[Category: Jeong, E Y]]
[[Category: Jeon W-J]]
[[Category: Kim, T G]]
[[Category: Jeong E-Y]]
[[Category: Ku, J K]]
[[Category: Kim TG]]
[[Category: Lee, S]]
[[Category: Ku JK]]
[[Category: Min, K I]]
[[Category: Lee S]]
[[Category: Song, K M]]
[[Category: Min KI]]
[[Category: Atp-binding]]
[[Category: Song K-M]]
[[Category: Cytoplasm]]
[[Category: Dna damage]]
[[Category: Dna recombination]]
[[Category: Dna repair]]
[[Category: Dna-binding]]
[[Category: Nucleotide-binding]]
[[Category: Recombination]]
[[Category: Sos response]]

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