3hlw: Difference between revisions

No edit summary
No edit summary
 
(One intermediate revision by the same user not shown)
Line 1: Line 1:


==CTX-M-9 S70G in complex with cefotaxime==
==CTX-M-9 S70G in complex with cefotaxime==
<StructureSection load='3hlw' size='340' side='right' caption='[[3hlw]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='3hlw' size='340' side='right'caption='[[3hlw]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3hlw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HLW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HLW FirstGlance]. <br>
<table><tr><td colspan='2'>[[3hlw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HLW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HLW FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CE3:(6R,7R)-3-(ACETYLOXYMETHYL)-7-[[(2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-METHOXYIMINO-ETHANOYL]AMINO]-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC+ACID'>CE3</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">blaCTX-M-9, blaCTX-M-9a, blaCTX-M-9b ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CE3:(6R,7R)-3-(ACETYLOXYMETHYL)-7-[[(2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-METHOXYIMINO-ETHANOYL]AMINO]-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC+ACID'>CE3</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hlw OCA], [http://pdbe.org/3hlw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hlw RCSB], [http://www.ebi.ac.uk/pdbsum/3hlw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hlw ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hlw OCA], [https://pdbe.org/3hlw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hlw RCSB], [https://www.ebi.ac.uk/pdbsum/3hlw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hlw ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9L5C8_ECOLX Q9L5C8_ECOLX]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 29: Line 31:


==See Also==
==See Also==
*[[Beta-lactamase|Beta-lactamase]]
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Bonnet, R]]
[[Category: Large Structures]]
[[Category: Delmas, J]]
[[Category: Bonnet R]]
[[Category: Dubois, D]]
[[Category: Delmas J]]
[[Category: Leyssne, D]]
[[Category: Dubois D]]
[[Category: Robin, F]]
[[Category: Leyssne D]]
[[Category: Vazeille, E]]
[[Category: Robin F]]
[[Category: Antibiotic resistance]]
[[Category: Vazeille E]]
[[Category: Beta-lactam]]
[[Category: Beta-lactamase]]
[[Category: Cefotaxime]]
[[Category: Cephalosporin]]
[[Category: Complex]]
[[Category: Ctx-m]]
[[Category: Ctx-m-9]]
[[Category: Esbl]]
[[Category: Hydrolase]]
[[Category: Michaeli]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA