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<StructureSection load='3daq' size='340' side='right'caption='[[3daq]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
<StructureSection load='3daq' size='340' side='right'caption='[[3daq]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3daq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staar Staar]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DAQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DAQ FirstGlance]. <br>
<table><tr><td colspan='2'>[[3daq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_MRSA252 Staphylococcus aureus subsp. aureus MRSA252]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DAQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DAQ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1yxc|1yxc]], [[1dhp|1dhp]], [[1xxx|1xxx]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dapA, SAR1407 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=282458 STAAR])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/4-hydroxy-tetrahydrodipicolinate_synthase 4-hydroxy-tetrahydrodipicolinate synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.3.3.7 4.3.3.7] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3daq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3daq OCA], [https://pdbe.org/3daq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3daq RCSB], [https://www.ebi.ac.uk/pdbsum/3daq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3daq ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3daq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3daq OCA], [https://pdbe.org/3daq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3daq RCSB], [https://www.ebi.ac.uk/pdbsum/3daq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3daq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/DAPA_STAAR DAPA_STAAR]] Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).<ref>PMID:18684709</ref>
[https://www.uniprot.org/uniprot/DAPA_STAAR DAPA_STAAR] Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).<ref>PMID:18684709</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: 4-hydroxy-tetrahydrodipicolinate synthase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Staar]]
[[Category: Staphylococcus aureus subsp. aureus MRSA252]]
[[Category: Burgess, B R]]
[[Category: Burgess BR]]
[[Category: Dobson, R C.J]]
[[Category: Dobson RCJ]]
[[Category: Gerrard, J A]]
[[Category: Gerrard JA]]
[[Category: Jameson, G B]]
[[Category: Jameson GB]]
[[Category: Parker, M W]]
[[Category: Parker MW]]
[[Category: Perugini, M A]]
[[Category: Perugini MA]]
[[Category: Amino-acid biosynthesis]]
[[Category: Diaminopimelate biosynthesis]]
[[Category: Dihydrodipicolinate synthase]]
[[Category: Lyase]]
[[Category: Lysine biosynthesis]]
[[Category: Schiff base]]

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