3cpj: Difference between revisions

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==Crystal structure of Ypt31 in complex with yeast Rab-GDI==
==Crystal structure of Ypt31 in complex with yeast Rab-GDI==
<StructureSection load='3cpj' size='340' side='right' caption='[[3cpj]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
<StructureSection load='3cpj' size='340' side='right'caption='[[3cpj]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3cpj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CPJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CPJ FirstGlance]. <br>
<table><tr><td colspan='2'>[[3cpj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CPJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CPJ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3cph|3cph]], [[3cpi|3cpi]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cpj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cpj OCA], [http://pdbe.org/3cpj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3cpj RCSB], [http://www.ebi.ac.uk/pdbsum/3cpj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3cpj ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cpj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cpj OCA], [https://pdbe.org/3cpj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cpj RCSB], [https://www.ebi.ac.uk/pdbsum/3cpj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cpj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GDI1_YEAST GDI1_YEAST]] Regulates the GDP/GTP exchange reaction of SEC4 by inhibiting the dissociation of GDP from it, and the subsequent binding of GTP to SEC4. Plays an essential role in the yeast secretory pathway.<ref>PMID:8157010</ref> [[http://www.uniprot.org/uniprot/YPT31_YEAST YPT31_YEAST]] Required for protein transport in the secretory pathway. Probably involved in regulation of secretory vesicle formation at the trans-Golgi compartment.<ref>PMID:8978673</ref> <ref>PMID:9151665</ref> 
[https://www.uniprot.org/uniprot/GDI1_YEAST GDI1_YEAST] Regulates the GDP/GTP exchange reaction of SEC4 by inhibiting the dissociation of GDP from it, and the subsequent binding of GTP to SEC4. Plays an essential role in the yeast secretory pathway.<ref>PMID:8157010</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[GTP-binding protein|GTP-binding protein]]
*[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 18824]]
[[Category: Large Structures]]
[[Category: Goody, R S]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Ignatev, A]]
[[Category: Goody RS]]
[[Category: Kravchenko, S]]
[[Category: Ignatev A]]
[[Category: Pylypenko, O]]
[[Category: Kravchenko S]]
[[Category: Rak, A]]
[[Category: Pylypenko O]]
[[Category: Acetylation]]
[[Category: Rak A]]
[[Category: Cytoplasm]]
[[Category: Golgi apparatus]]
[[Category: Gtp-binding]]
[[Category: Gtpase activation]]
[[Category: Lipoprotein]]
[[Category: Membrane]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Prenylation]]
[[Category: Protein transport]]
[[Category: Rab gtpase]]
[[Category: Vesicular transport]]

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