3c06: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| (One intermediate revision by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Lactobacillus CASEI Thymidylate Synthase Ternary Complex With DUMP and the Phtalimidic Derivative 14C in Multiple Binding Modes-Mode 1== | ==Lactobacillus CASEI Thymidylate Synthase Ternary Complex With DUMP and the Phtalimidic Derivative 14C in Multiple Binding Modes-Mode 1== | ||
<StructureSection load='3c06' size='340' side='right' caption='[[3c06]], [[Resolution|resolution]] 2.60Å' scene=''> | <StructureSection load='3c06' size='340' side='right'caption='[[3c06]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3c06]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3c06]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lacticaseibacillus_casei Lacticaseibacillus casei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C06 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C06 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=14C:2-(2-CHLOROPYRIDIN-4-YL)-4-METHYL-1H-ISOINDOLE-1,3(2H)-DIONE'>14C</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=14C:2-(2-CHLOROPYRIDIN-4-YL)-4-METHYL-1H-ISOINDOLE-1,3(2H)-DIONE'>14C</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c06 OCA], [https://pdbe.org/3c06 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c06 RCSB], [https://www.ebi.ac.uk/pdbsum/3c06 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c06 ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/TYSY_LACCA TYSY_LACCA] Provides the sole de novo source of dTMP for DNA biosynthesis. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 32: | Line 31: | ||
==See Also== | ==See Also== | ||
*[[Thymidylate synthase|Thymidylate synthase]] | *[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Lacticaseibacillus casei]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Cancian | [[Category: Cancian L]] | ||
[[Category: Costi | [[Category: Costi MP]] | ||
[[Category: Ferrari | [[Category: Ferrari S]] | ||
[[Category: Leone | [[Category: Leone R]] | ||
[[Category: Luciani | [[Category: Luciani R]] | ||
[[Category: Mangani | [[Category: Mangani S]] | ||