3bp8: Difference between revisions

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 ==Crystal structure of Mlc/EIIB complex==
-<StructureSection load='3bp8' size='340' side='right' caption='[[3bp8]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
+<StructureSection load='3bp8' size='340' side='right'caption='[[3bp8]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3bp8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BP8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BP8 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3bp8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BP8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BP8 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85&#8491;</td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mlc ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli]), ptsG, glcA, umg ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bp8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bp8 OCA], [http://pdbe.org/3bp8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3bp8 RCSB], [http://www.ebi.ac.uk/pdbsum/3bp8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3bp8 ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bp8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bp8 OCA], [https://pdbe.org/3bp8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bp8 RCSB], [https://www.ebi.ac.uk/pdbsum/3bp8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bp8 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/PTGCB_ECOLI PTGCB_ECOLI]] The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport. This enzyme is also a chemoreceptor monitoring the environment for changes in sugar concentration.
+[https://www.uniprot.org/uniprot/MLC_ECOLI MLC_ECOLI] Transcriptional repressor that regulates the expression of proteins that are part of the phosphotransferase system for sugar uptake. Regulates the expression of malT.<ref>PMID:10464268</ref> <ref>PMID:11361067</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bp/3bp8_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bp/3bp8_consurf.spt"</scriptWhenChecked>
      <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
@@ Line 31: / Line 31: @@
 ==See Also==
-*[[Phosphotransferase|Phosphotransferase]]
+*[[Phosphotransferase 3D structures|Phosphotransferase 3D structures]]
 == References ==
 <references/>
@@ Line 37: / Line 37: @@
 </StructureSection>
 [[Category: Escherichia coli]]
-[[Category: An, Y J]]
+[[Category: Large Structures]]
-[[Category: Cha, S S]]
+[[Category: An YJ]]
-[[Category: Jung, H I]]
+[[Category: Cha SS]]
-[[Category: Enzyme]]
+[[Category: Jung HI]]
-[[Category: Glucose signaling]]
-[[Category: Iicbglc]]
-[[Category: Inner membrane]]
-[[Category: Kinase]]
-[[Category: Membrane]]
-[[Category: Mlc]]
-[[Category: Phosphoprotein]]
-[[Category: Phosphotransferase system]]
-[[Category: Protein-protein interaction]]
-[[Category: Sugar transport]]
-[[Category: Transcription]]
-[[Category: Transcription regulation]]
-[[Category: Transferase]]
-[[Category: Transmembrane]]
-[[Category: Transport]]