3azf: Difference between revisions

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OCA

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 ==Crystal Structure of Human Nucleosome Core Particle Containing H3K79Q mutation==
-<StructureSection load='3azf' size='340' side='right' caption='[[3azf]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
+<StructureSection load='3azf' size='340' side='right'caption='[[3azf]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3azf]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AZF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AZF FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3azf]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AZF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AZF FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3afa|3afa]], [[3ayw|3ayw]], [[3aze|3aze]], [[3azg|3azg]], [[3azh|3azh]], [[3azi|3azi]], [[3azj|3azj]], [[3azk|3azk]], [[3azl|3azl]], [[3azm|3azm]], [[3azn|3azn]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3azf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3azf OCA], [http://pdbe.org/3azf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3azf RCSB], [http://www.ebi.ac.uk/pdbsum/3azf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3azf ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3azf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3azf OCA], [https://pdbe.org/3azf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3azf RCSB], [https://www.ebi.ac.uk/pdbsum/3azf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3azf ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/H2B1J_HUMAN H2B1J_HUMAN]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.<ref>PMID:11859126</ref> <ref>PMID:12860195</ref> <ref>PMID:15019208</ref>   Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.<ref>PMID:11859126</ref> <ref>PMID:12860195</ref> <ref>PMID:15019208</ref>
+[https://www.uniprot.org/uniprot/H31_HUMAN H31_HUMAN]
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 21: / Line 21: @@
 ==See Also==
-*[[Histone|Histone]]
+*[[Histone 3D structures|Histone 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
-[[Category: Iwasaki, W]]
+[[Category: Large Structures]]
-[[Category: Kagawa, W]]
+[[Category: Iwasaki W]]
-[[Category: Kawaguchi, K]]
+[[Category: Kagawa W]]
-[[Category: Kurumizaka, H]]
+[[Category: Kawaguchi K]]
-[[Category: Shibata, T]]
+[[Category: Kurumizaka H]]
-[[Category: Tachiwana, H]]
+[[Category: Shibata T]]
-[[Category: Histone-fold]]
+[[Category: Tachiwana H]]
-[[Category: Nucleosome]]
-[[Category: Structural protein-dna complex]]