3a1p: Difference between revisions

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==Structure of Ribosome maturation protein RimM and Ribosomal protein S19==
==Structure of Ribosome maturation protein RimM and Ribosomal protein S19==
<StructureSection load='3a1p' size='340' side='right' caption='[[3a1p]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='3a1p' size='340' side='right'caption='[[3a1p]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3a1p]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A1P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3A1P FirstGlance]. <br>
<table><tr><td colspan='2'>[[3a1p]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A1P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A1P FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2dyi|2dyi]], [[2e5l|2e5l]], [[2dog|2dog]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rimM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8]), rpsS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a1p OCA], [https://pdbe.org/3a1p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a1p RCSB], [https://www.ebi.ac.uk/pdbsum/3a1p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a1p ProSAT], [https://www.topsan.org/Proteins/RSGI/3a1p TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a1p OCA], [http://pdbe.org/3a1p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3a1p RCSB], [http://www.ebi.ac.uk/pdbsum/3a1p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3a1p ProSAT], [http://www.topsan.org/Proteins/RSGI/3a1p TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RIMM_THET8 RIMM_THET8]] An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity). [[http://www.uniprot.org/uniprot/RS19_THET8 RS19_THET8]] Located at the top of the head of the 30S subunit, extending towards the 50S subunit, which it may contact in the 70S complex. Contacts several RNA helices of the 16S rRNA.[HAMAP-Rule:MF_00531]
[https://www.uniprot.org/uniprot/RIMM_THET8 RIMM_THET8] An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a1/3a1p_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a1/3a1p_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Thet8]]
[[Category: Large Structures]]
[[Category: Kaminishi, T]]
[[Category: Thermus thermophilus HB8]]
[[Category: Kawazoe, M]]
[[Category: Kaminishi T]]
[[Category: Structural genomic]]
[[Category: Kawazoe M]]
[[Category: Shirouzu, M]]
[[Category: Shirouzu M]]
[[Category: Takemoto, C]]
[[Category: Takemoto C]]
[[Category: Tatsuguchi, A]]
[[Category: Tatsuguchi A]]
[[Category: Yokoyama, S]]
[[Category: Yokoyama S]]
[[Category: 16s rrna processing]]
[[Category: 30s ribosomal subunit]]
[[Category: Beta barrel]]
[[Category: Chaperone]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Prc-barrel domain]]
[[Category: Protein-protein complex]]
[[Category: Ribonucleoprotein]]
[[Category: Ribosomal protein]]
[[Category: Ribosome]]
[[Category: Ribosome biogenesis]]
[[Category: Rimm n-terminal domain]]
[[Category: Rna-binding]]
[[Category: Rrna binding]]
[[Category: Rsgi]]

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