3a1m: Difference between revisions
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< | ==A fusion protein of a beta helix region of gene product 5 and the foldon region of bacteriophage T4== | ||
<StructureSection load='3a1m' size='340' side='right'caption='[[3a1m]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3a1m]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A1M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A1M FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a1m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a1m OCA], [https://pdbe.org/3a1m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a1m RCSB], [https://www.ebi.ac.uk/pdbsum/3a1m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a1m ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/WAC_BPT4 WAC_BPT4] Chaperone responsible for attachment of long tail fibers to virus particle. Forms the fibrous structure on the neck of the virion called whiskers. During phage assembly, 6 fibritin molecules attach to each virion neck through their N-terminal domains, to form a collar with six fibers ('whiskers').[https://www.uniprot.org/uniprot/NEEDL_BPT4 NEEDL_BPT4] Tail-associated lysozyme of the baseplate hub that is essential for localized hydrolysis of bacterial cell wall necessary for viral DNA injection. The needle-like gp5 protein punctures the outer cell membrane and then digests the peptidoglycan cell wall in the periplasmic space. Involved in the tail assembly.<ref>PMID:12837775</ref> <ref>PMID:21129200</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a1/3a1m_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3a1m ConSurf]. | |||
<div style="clear:both"></div> | |||
== | ==See Also== | ||
*[[Fibritin|Fibritin]] | |||
== References == | |||
<references/> | |||
[[ | __TOC__ | ||
</StructureSection> | |||
== | [[Category: Escherichia virus T4]] | ||
< | [[Category: Large Structures]] | ||
[[Category: | [[Category: Arisaka F]] | ||
[[Category: | [[Category: Hikage T]] | ||
[[Category: Arisaka | [[Category: Kanamaru S]] | ||
[[Category: Hikage | [[Category: Koshiyama T]] | ||
[[Category: Kanamaru | [[Category: Suzuki A]] | ||
[[Category: Koshiyama | [[Category: Terauchi M]] | ||
[[Category: Suzuki | [[Category: Ueno T]] | ||
[[Category: Terauchi | [[Category: Watanabe Y]] | ||
[[Category: Ueno | [[Category: Yamane T]] | ||
[[Category: Watanabe | [[Category: Yokoi N]] | ||
[[Category: Yamane | [[Category: Yutani K]] | ||
[[Category: Yokoi | |||
[[Category: Yutani | |||
Latest revision as of 17:07, 1 November 2023
A fusion protein of a beta helix region of gene product 5 and the foldon region of bacteriophage T4A fusion protein of a beta helix region of gene product 5 and the foldon region of bacteriophage T4
Structural highlights
FunctionWAC_BPT4 Chaperone responsible for attachment of long tail fibers to virus particle. Forms the fibrous structure on the neck of the virion called whiskers. During phage assembly, 6 fibritin molecules attach to each virion neck through their N-terminal domains, to form a collar with six fibers ('whiskers').NEEDL_BPT4 Tail-associated lysozyme of the baseplate hub that is essential for localized hydrolysis of bacterial cell wall necessary for viral DNA injection. The needle-like gp5 protein punctures the outer cell membrane and then digests the peptidoglycan cell wall in the periplasmic space. Involved in the tail assembly.[1] [2] Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See AlsoReferences
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