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| ==Recombinant thiocyanate hydrolase, air-oxidized form of holo-enzyme== | | ==Recombinant thiocyanate hydrolase, air-oxidized form of holo-enzyme== |
| <StructureSection load='2zzd' size='340' side='right' caption='[[2zzd]], [[Resolution|resolution]] 1.78Å' scene=''> | | <StructureSection load='2zzd' size='340' side='right'caption='[[2zzd]], [[Resolution|resolution]] 1.78Å' scene=''> |
| == Structural highlights == | | == Structural highlights == |
| <table><tr><td colspan='2'>[[2zzd]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_thiocyanoxidans"_happold_and_key_1937 "bacterium thiocyanoxidans" happold and key 1937]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZZD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZZD FirstGlance]. <br> | | <table><tr><td colspan='2'>[[2zzd]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Thiobacillus_thioparus Thiobacillus thioparus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZZD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZZD FirstGlance]. <br> |
| </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3CO:COBALT+(III)+ION'>3CO</scene>, <scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr> | | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.78Å</td></tr> |
| <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr> | | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3CO:COBALT+(III)+ION'>3CO</scene>, <scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr> |
| <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2dd4|2dd4]], [[2dd5|2dd5]], [[2dxb|2dxb]], [[2dxc|2dxc]]</td></tr>
| | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zzd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zzd OCA], [https://pdbe.org/2zzd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zzd RCSB], [https://www.ebi.ac.uk/pdbsum/2zzd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zzd ProSAT]</span></td></tr> |
| <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">scnA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=931 "Bacterium thiocyanoxidans" Happold and Key 1937]), scnB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=931 "Bacterium thiocyanoxidans" Happold and Key 1937]), scnC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=931 "Bacterium thiocyanoxidans" Happold and Key 1937])</td></tr>
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| <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thiocyanate_hydrolase Thiocyanate hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.5.8 3.5.5.8] </span></td></tr> | |
| <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zzd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zzd OCA], [http://pdbe.org/2zzd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zzd RCSB], [http://www.ebi.ac.uk/pdbsum/2zzd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zzd ProSAT]</span></td></tr> | |
| </table> | | </table> |
| == Function == | | == Function == |
| [[http://www.uniprot.org/uniprot/SCNA_THITI SCNA_THITI]] Involved in the degradation of thiocyanate. [[http://www.uniprot.org/uniprot/SCNC_THITI SCNC_THITI]] Involved in the degradation of thiocyanate. [[http://www.uniprot.org/uniprot/SCNB_THITI SCNB_THITI]] Involved in the degradation of thiocyanate. | | [https://www.uniprot.org/uniprot/SCNA_THITI SCNA_THITI] Involved in the degradation of thiocyanate. |
| == Evolutionary Conservation == | | == Evolutionary Conservation == |
| [[Image:Consurf_key_small.gif|200px|right]] | | [[Image:Consurf_key_small.gif|200px|right]] |
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| __TOC__ | | __TOC__ |
| </StructureSection> | | </StructureSection> |
| [[Category: Bacterium thiocyanoxidans happold and key 1937]] | | [[Category: Large Structures]] |
| [[Category: Thiocyanate hydrolase]] | | [[Category: Thiobacillus thioparus]] |
| [[Category: Arakawa, T]] | | [[Category: Arakawa T]] |
| [[Category: Katayama, Y]] | | [[Category: Katayama Y]] |
| [[Category: Kawano, Y]] | | [[Category: Kawano Y]] |
| [[Category: Odaka, M]] | | [[Category: Odaka M]] |
| [[Category: Yohda, M]] | | [[Category: Yohda M]] |
| [[Category: Air inactivation]]
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| [[Category: Autocatalytic activation]]
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| [[Category: Carbonyl sulfide]]
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| [[Category: Claw setting]]
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| [[Category: Cobalt]]
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| [[Category: Complex]]
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| [[Category: Cysteine]]
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| [[Category: Enzyme]]
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| [[Category: Hydrolase]]
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| [[Category: Metal-binding]]
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| [[Category: Metalloprotein]]
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| [[Category: Model complex]]
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| [[Category: Nitrile hydratase]]
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| [[Category: Non-corrin]]
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| [[Category: Oxidation]]
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| [[Category: Post-translational modification]]
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| [[Category: Protein]]
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| [[Category: Scnase]]
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| [[Category: Sulfenate]]
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| [[Category: Sulfenic acid]]
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| [[Category: Sulfinate]]
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| [[Category: Sulfinic acid]]
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| [[Category: Thiocyanate]]
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