2zw2: Difference between revisions

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[[Image:2zw2.png|left|200px]]


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==Crystal Structure of Formylglycinamide Ribonucleotide Amidotransferase III from SULFOLOBUS TOKODAII (STPURS)==
The line below this paragraph, containing "STRUCTURE_2zw2", creates the "Structure Box" on the page.
<StructureSection load='2zw2' size='340' side='right'caption='[[2zw2]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2zw2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfurisphaera_tokodaii Sulfurisphaera tokodaii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZW2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZW2 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
{{STRUCTURE_2zw2|  PDB=2zw2  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zw2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zw2 OCA], [https://pdbe.org/2zw2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zw2 RCSB], [https://www.ebi.ac.uk/pdbsum/2zw2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zw2 ProSAT]</span></td></tr>
 
</table>
===Crystal Structure of Formylglycinamide Ribonucleotide Amidotransferase III from SULFOLOBUS TOKODAII (STPURS)===
== Function ==
 
[https://www.uniprot.org/uniprot/F9VNF4_SULTO F9VNF4_SULTO] Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.[HAMAP-Rule:MF_01926]
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
2ZW2 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Sulfolobus_tokodaii Sulfolobus tokodaii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZW2 OCA].  
Check<jmol>
[[Category: Phosphoribosylformylglycinamidine synthase]]
  <jmolCheckbox>
[[Category: Sulfolobus tokodaii]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zw/2zw2_consurf.spt"</scriptWhenChecked>
[[Category: Baba, S.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Kawai, G.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Kumasaka, T.]]
  </jmolCheckbox>
[[Category: Kuramitsu, S.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zw2 ConSurf].
[[Category: Masui, R.]]
<div style="clear:both"></div>
[[Category: Nakagawa, N.]]
__TOC__
[[Category: Okada, K.]]
</StructureSection>
[[Category: Sampei, G.]]
[[Category: Large Structures]]
[[Category: Suzuki, S.]]
[[Category: Sulfurisphaera tokodaii]]
[[Category: Tamura, S.]]
[[Category: Baba S]]
[[Category: Ligase]]
[[Category: Kawai G]]
[[Category: Purine metabolism]]
[[Category: Kumasaka T]]
 
[[Category: Kuramitsu S]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 28 14:36:36 2010''
[[Category: Masui R]]
[[Category: Nakagawa N]]
[[Category: Okada K]]
[[Category: Sampei G]]
[[Category: Suzuki S]]
[[Category: Tamura S]]

Latest revision as of 16:58, 1 November 2023

Crystal Structure of Formylglycinamide Ribonucleotide Amidotransferase III from SULFOLOBUS TOKODAII (STPURS)Crystal Structure of Formylglycinamide Ribonucleotide Amidotransferase III from SULFOLOBUS TOKODAII (STPURS)

Structural highlights

2zw2 is a 2 chain structure with sequence from Sulfurisphaera tokodaii. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.55Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

F9VNF4_SULTO Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.[HAMAP-Rule:MF_01926]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2zw2, resolution 1.55Å

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