2zkc: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-'''Unreleased structure'''
-The entry 2zkc is ON HOLD  until Paper Publication
+==Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with bisphenol Z==
+<StructureSection load='2zkc' size='340' side='right'caption='[[2zkc]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2zkc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZKC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZKC FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BPZ:4,4-CYCLOHEXANE-1,1-DIYLDIPHENOL'>BPZ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zkc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zkc OCA], [https://pdbe.org/2zkc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zkc RCSB], [https://www.ebi.ac.uk/pdbsum/2zkc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zkc ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ERR3_HUMAN ERR3_HUMAN] Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements (By similarity).<ref>PMID:19067653</ref> <ref>PMID:18063693</ref> <ref>PMID:11864604</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zk/2zkc_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zkc ConSurf].
+<div style="clear:both"></div>
-Authors: Matsushima, A., Kakuta, Y., Teramoto, T., Shimohigashi, Y.
+==See Also==
+*[[Estrogen-related receptor 3D structures|Estrogen-related receptor 3D structures]]
-Description: Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with bisphenol Z
+== References ==
+<references/>
+__TOC__
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 11 09:18:59 2008''
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Kakuta Y]]
+[[Category: Matsushima A]]
+[[Category: Shimohigashi Y]]
+[[Category: Teramoto T]]