2z3w: Difference between revisions

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==Prolyl tripeptidyl aminopeptidase mutant E636A==
==Prolyl tripeptidyl aminopeptidase mutant E636A==
<StructureSection load='2z3w' size='340' side='right' caption='[[2z3w]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='2z3w' size='340' side='right'caption='[[2z3w]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2z3w]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Porgi Porgi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z3W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z3W FirstGlance]. <br>
<table><tr><td colspan='2'>[[2z3w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Porphyromonas_gingivalis_W83 Porphyromonas gingivalis W83]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z3W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z3W FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2d5l|2d5l]], [[2dcm|2dcm]], [[2eep|2eep]], [[2z3z|2z3z]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PG1361 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=242619 PORGI])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z3w OCA], [https://pdbe.org/2z3w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z3w RCSB], [https://www.ebi.ac.uk/pdbsum/2z3w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z3w ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z3w OCA], [http://pdbe.org/2z3w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2z3w RCSB], [http://www.ebi.ac.uk/pdbsum/2z3w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2z3w ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PTP_PORGI PTP_PORGI]] Serine proteinase. Releases tripeptides from the free amino terminus of proteins. Has a requirement for Pro in the P1 position, but is inactivated by Pro in the P1' position.<ref>PMID:10092598</ref>
[https://www.uniprot.org/uniprot/PTP_PORGI PTP_PORGI] Serine proteinase. Releases tripeptides from the free amino terminus of proteins. Has a requirement for Pro in the P1 position, but is inactivated by Pro in the P1' position.<ref>PMID:10092598</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Porgi]]
[[Category: Large Structures]]
[[Category: Ito, K]]
[[Category: Porphyromonas gingivalis W83]]
[[Category: Nakajima, Y]]
[[Category: Ito K]]
[[Category: Xu, Y]]
[[Category: Nakajima Y]]
[[Category: Yoshimoto, T]]
[[Category: Xu Y]]
[[Category: Hydrolase]]
[[Category: Yoshimoto T]]
[[Category: Peptidase family s9]]
[[Category: Proline-specific peptidase]]
[[Category: Prolyl oligopeptidase family]]
[[Category: Serine protease]]

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