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==Crystal Structure of tryptophanyl-tRNA synthetase from Mycoplasma pneumoniae==
==Crystal Structure of tryptophanyl-tRNA synthetase from Mycoplasma pneumoniae==
<StructureSection load='2yy5' size='340' side='right' caption='[[2yy5]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
<StructureSection load='2yy5' size='340' side='right'caption='[[2yy5]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2yy5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycoplasma_pneumoniae Mycoplasma pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YY5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YY5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2yy5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycoplasma_pneumoniae_M129 Mycoplasma pneumoniae M129]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YY5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YY5 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WSA:5-O-[(L-TRYPTOPHYLAMINO)SULFONYL]ADENOSINE'>WSA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tryptophan--tRNA_ligase Tryptophan--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.2 6.1.1.2] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WSA:5-O-[(L-TRYPTOPHYLAMINO)SULFONYL]ADENOSINE'>WSA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yy5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yy5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yy5 RCSB], [http://www.ebi.ac.uk/pdbsum/2yy5 PDBsum], [http://www.topsan.org/Proteins/RSGI/2yy5 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yy5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yy5 OCA], [https://pdbe.org/2yy5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yy5 RCSB], [https://www.ebi.ac.uk/pdbsum/2yy5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yy5 ProSAT], [https://www.topsan.org/Proteins/RSGI/2yy5 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SYW_MYCPN SYW_MYCPN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yy/2yy5_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yy/2yy5_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2yy5 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Aminoacyl tRNA Synthetase|Aminoacyl tRNA Synthetase]]
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Mycoplasma pneumoniae]]
[[Category: Large Structures]]
[[Category: Tryptophan--tRNA ligase]]
[[Category: Mycoplasma pneumoniae M129]]
[[Category: Bessho, Y]]
[[Category: Bessho Y]]
[[Category: Ishii, T]]
[[Category: Ishii T]]
[[Category: Structural genomic]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S]]
[[Category: Aminoaccyl trna synthetase]]
[[Category: Ligase]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Rsgi]]

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