2yv0: Difference between revisions

No edit summary
No edit summary
 
Line 3: Line 3:
<StructureSection load='2yv0' size='340' side='right'caption='[[2yv0]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
<StructureSection load='2yv0' size='340' side='right'caption='[[2yv0]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2yv0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YV0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YV0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2yv0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YV0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YV0 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rnhA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Ribonuclease_H Ribonuclease H], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.4 3.1.26.4] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yv0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yv0 OCA], [https://pdbe.org/2yv0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yv0 RCSB], [https://www.ebi.ac.uk/pdbsum/2yv0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yv0 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yv0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yv0 OCA], [https://pdbe.org/2yv0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yv0 RCSB], [https://www.ebi.ac.uk/pdbsum/2yv0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yv0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/RNH_ECOLI RNH_ECOLI]] Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. RNase H participates in DNA replication; it helps to specify the origin of genomic replication by suppressing initiation at origins other than the oriC locus; along with the 5'-3' exonuclease of pol1, it removes RNA primers from the Okazaki fragments of lagging strand synthesis; and it defines the origin of replication for ColE1-type plasmids by specific cleavage of an RNA preprimer.[HAMAP-Rule:MF_00042]  
[https://www.uniprot.org/uniprot/RNH_ECOLI RNH_ECOLI] Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. RNase H participates in DNA replication; it helps to specify the origin of genomic replication by suppressing initiation at origins other than the oriC locus; along with the 5'-3' exonuclease of pol1, it removes RNA primers from the Okazaki fragments of lagging strand synthesis; and it defines the origin of replication for ColE1-type plasmids by specific cleavage of an RNA preprimer.[HAMAP-Rule:MF_00042]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 36: Line 35:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Ribonuclease H]]
[[Category: Haruki M]]
[[Category: Haruki, M]]
[[Category: Kanaya S]]
[[Category: Kanaya, S]]
[[Category: Koga Y]]
[[Category: Koga, Y]]
[[Category: Motegi T]]
[[Category: Motegi, T]]
[[Category: Tadokoro T]]
[[Category: Tadokoro, T]]
[[Category: Takano K]]
[[Category: Takano, K]]
[[Category: E. coli]]
[[Category: Hydrolase]]
[[Category: Quintuple thermostabilizing mutation]]
[[Category: Rnase hi]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA