2ri4: Difference between revisions

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{{Seed}}
[[Image:2ri4.png|left|200px]]


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==Crystal Structure determination of Goat Methemoglobin at 2.7 Angstrom==
The line below this paragraph, containing "STRUCTURE_2ri4", creates the "Structure Box" on the page.
<StructureSection load='2ri4' size='340' side='right'caption='[[2ri4]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2ri4]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Capra_hircus Capra hircus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RI4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RI4 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
{{STRUCTURE_2ri4| PDB=2ri4 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ri4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ri4 OCA], [https://pdbe.org/2ri4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ri4 RCSB], [https://www.ebi.ac.uk/pdbsum/2ri4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ri4 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HBA1_CAPHI HBA1_CAPHI] Involved in oxygen transport from the lung to the various peripheral tissues.  Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1. Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.[UniProtKB:P01946]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ri/2ri4_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ri4 ConSurf].
<div style="clear:both"></div>


===Crystal Structure determination of Goat Methemoglobin at 2.7 Angstrom===
==See Also==
 
*[[Hemoglobin 3D structures|Hemoglobin 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2RI4 is a 8 chains structure with sequences from [http://en.wikipedia.org/wiki/Capra_hircus Capra hircus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RI4 OCA].
 
==Reference==
<ref group="xtra">PMID:17909297</ref><references group="xtra"/>
[[Category: Capra hircus]]
[[Category: Capra hircus]]
[[Category: Balasubramanian, M.]]
[[Category: Large Structures]]
[[Category: Moorthy, Pon Sathya.]]
[[Category: Balasubramanian M]]
[[Category: Neelagandan, K.]]
[[Category: Neelagandan K]]
[[Category: Ponnuswamy, M N.]]
[[Category: Ponnuswamy MN]]
[[Category: Allosteric mechanism]]
[[Category: Sathya Moorthy P]]
[[Category: Heme]]
[[Category: Iron]]
[[Category: Low oxygen affinity]]
[[Category: Metal-binding]]
[[Category: Methemoglobin]]
[[Category: Oxygen storage]]
[[Category: Oxygen transport]]
[[Category: Polymorphism]]
[[Category: Transport]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr  7 10:09:26 2010''

Latest revision as of 12:04, 25 October 2023

Crystal Structure determination of Goat Methemoglobin at 2.7 AngstromCrystal Structure determination of Goat Methemoglobin at 2.7 Angstrom

Structural highlights

2ri4 is a 8 chain structure with sequence from Capra hircus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.7Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

HBA1_CAPHI Involved in oxygen transport from the lung to the various peripheral tissues. Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1. Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.[UniProtKB:P01946]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2ri4, resolution 2.70Å

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