2pcl: Difference between revisions

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[[Image:2pcl.jpg|left|200px]]


{{Structure
==Crystal structure of ABC transporter with complex (aq_297) from aquifex aeolicus VF5==
|PDB= 2pcl |SIZE=350|CAPTION= <scene name='initialview01'>2pcl</scene>, resolution 1.70&Aring;
<StructureSection load='2pcl' size='340' side='right'caption='[[2pcl]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>
<table><tr><td colspan='2'>[[2pcl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PCL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PCL FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pcl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pcl OCA], [https://pdbe.org/2pcl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pcl RCSB], [https://www.ebi.ac.uk/pdbsum/2pcl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pcl ProSAT], [https://www.topsan.org/Proteins/RSGI/2pcl TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LOLD_AQUAE LOLD_AQUAE] Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pc/2pcl_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pcl ConSurf].
<div style="clear:both"></div>


'''Crystal structure of ABC transporter with complex (aq_297) from aquifex aeolicus VF5'''
==See Also==
 
*[[ABC transporter 3D structures|ABC transporter 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2PCL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PCL OCA].
[[Category: Aquifex aeolicus VF5]]
[[Category: Aquifex aeolicus]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Ebihara A]]
[[Category: Ebihara, A.]]
[[Category: Jeyakanthan J]]
[[Category: Jeyakanthan, J.]]
[[Category: Kanaujia SP]]
[[Category: Kanaujia, S P.]]
[[Category: Kuramitsu S]]
[[Category: Kuramitsu, S.]]
[[Category: Nakagawa N]]
[[Category: Nakagawa, N.]]
[[Category: Rafi ZA]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Sekar K]]
[[Category: Rafi, Z A.]]
[[Category: Shinkai A]]
[[Category: Sekar, K.]]
[[Category: Shiro Y]]
[[Category: Shinkai, A.]]
[[Category: Yokoyama S]]
[[Category: Shiro, Y.]]
[[Category: Yokoyama, S.]]
[[Category: EDO]]
[[Category: MG]]
[[Category: SO4]]
[[Category: abc transporter]]
[[Category: atp-binding protein]]
[[Category: hydrolase]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
 
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