2pcl: Difference between revisions

New page: left|200px<br /><applet load="2pcl" size="350" color="white" frame="true" align="right" spinBox="true" caption="2pcl, resolution 1.70Å" /> '''Crystal structure of...
 
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[[Image:2pcl.jpg|left|200px]]<br /><applet load="2pcl" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2pcl, resolution 1.70&Aring;" />
'''Crystal structure of ABC transporter with complex (aq_297) from aquifex aeolicus VF5'''<br />


==About this Structure==
==Crystal structure of ABC transporter with complex (aq_297) from aquifex aeolicus VF5==
2PCL is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=EDO:'>EDO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PCL OCA].
<StructureSection load='2pcl' size='340' side='right'caption='[[2pcl]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
[[Category: Aquifex aeolicus]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[2pcl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PCL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PCL FirstGlance]. <br>
[[Category: Ebihara, A.]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
[[Category: Jeyakanthan, J.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[Category: Kanaujia, S.P.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pcl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pcl OCA], [https://pdbe.org/2pcl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pcl RCSB], [https://www.ebi.ac.uk/pdbsum/2pcl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pcl ProSAT], [https://www.topsan.org/Proteins/RSGI/2pcl TOPSAN]</span></td></tr>
[[Category: Kuramitsu, S.]]
</table>
[[Category: Nakagawa, N.]]
== Function ==
[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
[https://www.uniprot.org/uniprot/LOLD_AQUAE LOLD_AQUAE] Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity).
[[Category: Rafi, Z.A.]]
== Evolutionary Conservation ==
[[Category: Sekar, K.]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Shinkai, A.]]
Check<jmol>
[[Category: Shiro, Y.]]
  <jmolCheckbox>
[[Category: Yokoyama, S.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pc/2pcl_consurf.spt"</scriptWhenChecked>
[[Category: EDO]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: MG]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: SO4]]
  </jmolCheckbox>
[[Category: abc transporter]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pcl ConSurf].
[[Category: atp-binding protein]]
<div style="clear:both"></div>
[[Category: hydrolase]]
[[Category: national project on protein structural and functional analyses]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomics]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 13:20:15 2008''
==See Also==
*[[ABC transporter 3D structures|ABC transporter 3D structures]]
__TOC__
</StructureSection>
[[Category: Aquifex aeolicus VF5]]
[[Category: Large Structures]]
[[Category: Ebihara A]]
[[Category: Jeyakanthan J]]
[[Category: Kanaujia SP]]
[[Category: Kuramitsu S]]
[[Category: Nakagawa N]]
[[Category: Rafi ZA]]
[[Category: Sekar K]]
[[Category: Shinkai A]]
[[Category: Shiro Y]]
[[Category: Yokoyama S]]

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