2oe2: Difference between revisions

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 <StructureSection load='2oe2' size='340' side='right'caption='[[2oe2]], [[Resolution|resolution]] 3.45&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2oe2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_smegmatis"_trevisan_1889 "bacillus smegmatis" trevisan 1889]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OE2 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2OE2 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2oe2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis Mycolicibacterium smegmatis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OE2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OE2 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.45&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ubc|1ubc]], [[2odn|2odn]], [[2odw|2odw]], [[2oep|2oep]], [[2oes|2oes]], [[2ofo|2ofo]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Deleted_entry Deleted entry], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.99.37 3.4.99.37] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oe2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oe2 OCA], [https://pdbe.org/2oe2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oe2 RCSB], [https://www.ebi.ac.uk/pdbsum/2oe2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oe2 ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2oe2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oe2 OCA], [http://pdbe.org/2oe2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2oe2 RCSB], [http://www.ebi.ac.uk/pdbsum/2oe2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2oe2 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/RECA_MYCS2 RECA_MYCS2]] Required for homologous recombination (HR) and the bypass of mutagenic DNA lesions (double strand breaks, DSB) by the SOS response. Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. Numerous X-ray crystals have been resolved under different conditions which indicate the flexibility of the protein, essential to its function. Gln-196 contributes to this plasticity by acting as a switch residue, which transmits the effect of nucleotide binding to the DNA-binding region.<ref>PMID:17360246</ref> <ref>PMID:17496093</ref> <ref>PMID:21219454</ref>
+[https://www.uniprot.org/uniprot/Q5QJ16_MYCSM Q5QJ16_MYCSM] Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.[HAMAP-Rule:MF_00268]
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 32: / Line 31: @@
 ==See Also==
-*[[Recombinase A|Recombinase A]]
+*[[3D structures of recombinase A|3D structures of recombinase A]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Bacillus smegmatis trevisan 1889]]
-[[Category: Deleted entry]]
 [[Category: Large Structures]]
-[[Category: Chandra, N R]]
+[[Category: Mycolicibacterium smegmatis]]
-[[Category: Datta, S]]
+[[Category: Chandra NR]]
-[[Category: Krishna, R]]
+[[Category: Datta S]]
-[[Category: Manjunath, G P]]
+[[Category: Krishna R]]
-[[Category: Muniyappa, K]]
+[[Category: Manjunath GP]]
-[[Category: Prabu, J Rajan]]
+[[Category: Muniyappa K]]
-[[Category: Vijayan, M]]
+[[Category: Rajan Prabu J]]
-[[Category: Dna-repair]]
+[[Category: Vijayan M]]
-[[Category: Recombination]]
-[[Category: Sos responce]]