2hvb: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-[[Image:2hvb.jpg|left|200px]]<br /><applet load="2hvb" size="450" color="white" frame="true" align="right" spinBox="true"
-caption="2hvb, resolution 2.50&Aring;" />
-'''Crystal structure of hypothetical protein PH1083 from Pyrococcus horikoshii OT3'''<br />
-==About this Structure==
+==Crystal structure of hypothetical protein PH1083 from Pyrococcus horikoshii OT3==
-HVB is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii] with FE as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Superoxide_reductase Superoxide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.2 1.15.1.2] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2HVB OCA].
+<StructureSection load='2hvb' size='340' side='right'caption='[[2hvb]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-[[Category: Pyrococcus horikoshii]]
+== Structural highlights ==
-[[Category: Single protein]]
+<table><tr><td colspan='2'>[[2hvb]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HVB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HVB FirstGlance]. <br>
-[[Category: Superoxide reductase]]
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-[[Category: Kunishima, N.]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
-[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hvb OCA], [https://pdbe.org/2hvb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hvb RCSB], [https://www.ebi.ac.uk/pdbsum/2hvb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hvb ProSAT], [https://www.topsan.org/Proteins/RSGI/2hvb TOPSAN]</span></td></tr>
-[[Category: Yamamoto, H.]]
+</table>
-[[Category: FE]]
+== Function ==
-[[Category: beta barrel fold]]
+[https://www.uniprot.org/uniprot/SOR_PYRHO SOR_PYRHO] Uses electrons from reduced NADP, by way of rubredoxin and an oxidoreductase, to catalyze the reduction of superoxide to hydrogen peroxide (By similarity).
-[[Category: national project on protein structural and functional analyses]]
+== Evolutionary Conservation ==
-[[Category: non-heme iron protein]]
+[[Image:Consurf_key_small.gif|200px|right]]
-[[Category: nppsfa]]
+Check<jmol>
-[[Category: riken structural genomics/proteomics initiative]]
+  <jmolCheckbox>
-[[Category: rsgi]]
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hv/2hvb_consurf.spt"</scriptWhenChecked>
-[[Category: structural genomics]]
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 12:00:28 2007''
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hvb ConSurf].
+<div style="clear:both"></div>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Pyrococcus horikoshii OT3]]
+[[Category: Kunishima N]]
+[[Category: Yamamoto H]]