2gnc: Difference between revisions

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 ==Crystal structure of srGAP1 SH3 domain in the slit-robo signaling pathway==
-<StructureSection load='2gnc' size='340' side='right' caption='[[2gnc]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
+<StructureSection load='2gnc' size='340' side='right'caption='[[2gnc]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2gnc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GNC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GNC FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2gnc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GNC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GNC FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gnc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gnc OCA], [http://pdbe.org/2gnc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2gnc RCSB], [http://www.ebi.ac.uk/pdbsum/2gnc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2gnc ProSAT]</span></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gnc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gnc OCA], [https://pdbe.org/2gnc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gnc RCSB], [https://www.ebi.ac.uk/pdbsum/2gnc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gnc ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/SRGP1_MOUSE SRGP1_MOUSE]] GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42 (By similarity).
+[https://www.uniprot.org/uniprot/SRGP1_MOUSE SRGP1_MOUSE] GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42 (By similarity).
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 29: / Line 30: @@
 ==See Also==
-*[[Rho GTPase activating protein|Rho GTPase activating protein]]
+*[[Rho GTPase activating protein 3D structures|Rho GTPase activating protein 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Lk3 transgenic mice]]
+[[Category: Large Structures]]
-[[Category: Bartlam, M]]
+[[Category: Mus musculus]]
-[[Category: Gao, F]]
+[[Category: Bartlam M]]
-[[Category: Li, X]]
+[[Category: Gao F]]
-[[Category: Liu, Y]]
+[[Category: Li X]]
-[[Category: Rao, Z]]
+[[Category: Liu Y]]
-[[Category: Wu, J Y]]
+[[Category: Rao Z]]
-[[Category: Beta barrel]]
+[[Category: Wu JY]]
-[[Category: Signaling protein]]