2f0z: Difference between revisions

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-{{Seed}}
-[[Image:2f0z.png|left|200px]]
-<!--
+==Crystal Structure of the Human Sialidase Neu2 in Complex with Zanamivir inhibitor==
-The line below this paragraph, containing "STRUCTURE_2f0z", creates the "Structure Box" on the page.
+<StructureSection load='2f0z' size='340' side='right'caption='[[2f0z]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2f0z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F0Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F0Z FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZMR:ZANAMIVIR'>ZMR</scene></td></tr>
-{{STRUCTURE_2f0z|  PDB=2f0z  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f0z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f0z OCA], [https://pdbe.org/2f0z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f0z RCSB], [https://www.ebi.ac.uk/pdbsum/2f0z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f0z ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/NEUR2_HUMAN NEUR2_HUMAN] Hydrolyzes sialylated compounds.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f0/2f0z_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f0z ConSurf].
+<div style="clear:both"></div>
-===Crystal Structure of the Human Sialidase Neu2 in Complex with Zanamivir inhibitor===
+==See Also==
+*[[Neuraminidase 3D structures|Neuraminidase 3D structures]]
+__TOC__
-==About this Structure==
+</StructureSection>
-F0Z is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F0Z OCA].
-[[Category: Exo-alpha-sialidase]]
 [[Category: Homo sapiens]]
-[[Category: Chavas, L M.G.]]
+[[Category: Large Structures]]
-[[Category: Colman, P M.]]
+[[Category: Chavas LMG]]
-[[Category: Fusi, P.]]
+[[Category: Colman PM]]
-[[Category: Kato, R.]]
+[[Category: Fusi P]]
-[[Category: McKimm-Breschkin, J.]]
+[[Category: Kato R]]
-[[Category: Monti, E.]]
+[[Category: McKimm-Breschkin J]]
-[[Category: Tettamanti, G.]]
+[[Category: Monti E]]
-[[Category: Tringali, C.]]
+[[Category: Tettamanti G]]
-[[Category: Venerando, B.]]
+[[Category: Tringali C]]
-[[Category: Wakatsuki, S.]]
+[[Category: Venerando B]]
-[[Category: Influenza virus]]
+[[Category: Wakatsuki S]]
-[[Category: Neuraminidase]]
-[[Category: Sialidase]]
-[[Category: Zanamivir]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 21:44:11 2009''