2ei0: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-[[Image:2ei0.jpg|left|200px]]<br /><applet load="2ei0" size="350" color="white" frame="true" align="right" spinBox="true"
-caption="2ei0, resolution 1.60&Aring;" />
-'''Anaerobic Crystal Structure Analysis of 1,2-dihydroxynaphthalene dioxygenase from Pseudomonas sp. strain C18 complexed with 3,4-dihydroxybiphenyl'''<br />
-==About this Structure==
+==Anaerobic Crystal Structure Analysis of 1,2-dihydroxynaphthalene dioxygenase from Pseudomonas sp. strain C18 complexed with 3,4-dihydroxybiphenyl==
-EI0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_sp. Pseudomonas sp.] with <scene name='pdbligand=FE2:'>FE2</scene>, <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=BP7:'>BP7</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Sites: <scene name='pdbsite=AC1:Fe2+Binding+Site+For+Residue+A+399'>AC1</scene>, <scene name='pdbsite=AC2:Mg+Binding+Site+For+Residue+A+398'>AC2</scene>, <scene name='pdbsite=AC3:Bp7+Binding+Site+For+Residue+A+400'>AC3</scene>, <scene name='pdbsite=AC4:Bp7+Binding+Site+For+Residue+A+401'>AC4</scene>, <scene name='pdbsite=AC5:Bp7+Binding+Site+For+Residue+A+402'>AC5</scene> and <scene name='pdbsite=AC6:Gol+Binding+Site+For+Residue+A+901'>AC6</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EI0 OCA].
+<StructureSection load='2ei0' size='340' side='right'caption='[[2ei0]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
-[[Category: Pseudomonas sp.]]
+== Structural highlights ==
-[[Category: Single protein]]
+<table><tr><td colspan='2'>[[2ei0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_sp._C18 Pseudomonas sp. C18]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EI0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EI0 FirstGlance]. <br>
-[[Category: Bolin, J T.]]
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-[[Category: Colbert, C L.]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BP7:1,1-BIPHENYL-3,4-DIOL'>BP7</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-[[Category: Kelker, M S.]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ei0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ei0 OCA], [https://pdbe.org/2ei0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ei0 RCSB], [https://www.ebi.ac.uk/pdbsum/2ei0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ei0 ProSAT]</span></td></tr>
-[[Category: Neau, D B.]]
+</table>
-[[Category: BP7]]
+== Function ==
-[[Category: FE2]]
+[https://www.uniprot.org/uniprot/NAHC_PSEU8 NAHC_PSEU8] Involved in the naphthalene catabolic pathway. Catalyzes the meta-cleavage of 1,2-dihydroxynaphthalene (1,2-DHN) to yield 2-hydroxychromene-2-carboxylic acid (By similarity).
-[[Category: GOL]]
+== Evolutionary Conservation ==
-[[Category: MG]]
+[[Image:Consurf_key_small.gif|200px|right]]
-[[Category: extradiol dioxygenase]]
+Check<jmol>
-[[Category: oxidoreductase]]
+  <jmolCheckbox>
-[[Category: protein substrate complex]]
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ei/2ei0_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ei0 ConSurf].
+<div style="clear:both"></div>
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:10:23 2008''
+==See Also==
+*[[Dioxygenase 3D structures|Dioxygenase 3D structures]]
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Pseudomonas sp. C18]]
+[[Category: Bolin JT]]
+[[Category: Colbert CL]]
+[[Category: Kelker MS]]
+[[Category: Neau DB]]