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==Crystal structure of intracellular family 1 beta-glucosidase BGL1A from the basidiomycete Phanerochaete chrysosporium in complex with gluconolactone==
==Crystal structure of intracellular family 1 beta-glucosidase BGL1A from the basidiomycete Phanerochaete chrysosporium in complex with gluconolactone==
<StructureSection load='2e40' size='340' side='right' caption='[[2e40]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='2e40' size='340' side='right'caption='[[2e40]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2e40]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Chrysosporium_pruinosum_(gilman_&_abbott)_carmich. Chrysosporium pruinosum (gilman & abbott) carmich.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E40 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E40 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2e40]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Phanerodontia_chrysosporium Phanerodontia chrysosporium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E40 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E40 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LGC:(3S,4R,5R,6S)-3,4,5-TRIHYDROXY-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-2-ONE'>LGC</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2e3z|2e3z]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LGC:(3S,4R,5R,6S)-3,4,5-TRIHYDROXY-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-2-ONE'>LGC</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">bgl1A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5306 Chrysosporium pruinosum (Gilman & Abbott) Carmich.])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e40 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e40 OCA], [https://pdbe.org/2e40 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e40 RCSB], [https://www.ebi.ac.uk/pdbsum/2e40 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e40 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-glucosidase Beta-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.21 3.2.1.21] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e40 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e40 OCA], [http://pdbe.org/2e40 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2e40 RCSB], [http://www.ebi.ac.uk/pdbsum/2e40 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2e40 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/BGL1A_PHACH BGL1A_PHACH]] Plays an important role in cellulose degradation. Shows hydrolytic activity against several glycosidic compounds.<ref>PMID:16896601</ref>
[https://www.uniprot.org/uniprot/BGL1A_PHACH BGL1A_PHACH] Plays an important role in cellulose degradation. Shows hydrolytic activity against several glycosidic compounds.<ref>PMID:16896601</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Beta-glucosidase|Beta-glucosidase]]
*[[Beta-glucosidase 3D structures|Beta-glucosidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Beta-glucosidase]]
[[Category: Large Structures]]
[[Category: Fushinobu, S]]
[[Category: Phanerodontia chrysosporium]]
[[Category: Igarashi, K]]
[[Category: Fushinobu S]]
[[Category: Nijikken, Y]]
[[Category: Igarashi K]]
[[Category: Samejima, M]]
[[Category: Nijikken Y]]
[[Category: Tsukada, T]]
[[Category: Samejima M]]
[[Category: Clan gh-a]]
[[Category: Tsukada T]]
[[Category: Glycoside hydrolase family 1]]
[[Category: Hydrolase]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Structural genomic]]
[[Category: Tim barrel]]

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