2dtt: Difference between revisions

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[[Image:2dtt.jpg|left|200px]]


{{Structure
==Crystal structure of 6-pyruvoyl tetrahydrobiopterin synthase from Pyrococcus horikoshii OT3 complexed with (1'R,2'S)-biopterin==
|PDB= 2dtt |SIZE=350|CAPTION= <scene name='initialview01'>2dtt</scene>, resolution 2.20&Aring;
<StructureSection load='2dtt' size='340' side='right'caption='[[2dtt]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=H4B:5,6,7,8-TETRAHYDROBIOPTERIN'>H4B</scene>
<table><tr><td colspan='2'>[[2dtt]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DTT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DTT FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
|GENE= PH0634 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=53953 Pyrococcus horikoshii])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=H4B:5,6,7,8-TETRAHYDROBIOPTERIN'>H4B</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dtt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dtt OCA], [https://pdbe.org/2dtt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dtt RCSB], [https://www.ebi.ac.uk/pdbsum/2dtt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dtt ProSAT], [https://www.topsan.org/Proteins/RSGI/2dtt TOPSAN]</span></td></tr>
|RELATEDENTRY=[[2dj6|2DJ6]]
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dtt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dtt OCA], [http://www.ebi.ac.uk/pdbsum/2dtt PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2dtt RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/O58368_PYRHO O58368_PYRHO]
 
== Evolutionary Conservation ==
'''Crystal structure of 6-pyruvoyl tetrahydrobiopterin synthase from Pyrococcus horikoshii OT3 complexed with (1'R,2'S)-biopterin'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dt/2dtt_consurf.spt"</scriptWhenChecked>
2DTT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DTT OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Pyrococcus horikoshii]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Single protein]]
  </jmolCheckbox>
[[Category: Bagautdinov, B.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dtt ConSurf].
[[Category: Kunishima, N.]]
<div style="clear:both"></div>
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
__TOC__
[[Category: 6-pyruvoyl tetrahydrobiopterin synthase (ptps)]]
</StructureSection>
[[Category: biopterin]]
[[Category: Large Structures]]
[[Category: national project on protein structural and functional analyse]]
[[Category: Pyrococcus horikoshii OT3]]
[[Category: nppsfa]]
[[Category: Bagautdinov B]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: Kunishima N]]
[[Category: rsgi]]
[[Category: structural genomic]]
[[Category: x-ray diffraction]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:39:22 2008''

Latest revision as of 11:29, 25 October 2023

Crystal structure of 6-pyruvoyl tetrahydrobiopterin synthase from Pyrococcus horikoshii OT3 complexed with (1'R,2'S)-biopterinCrystal structure of 6-pyruvoyl tetrahydrobiopterin synthase from Pyrococcus horikoshii OT3 complexed with (1'R,2'S)-biopterin

Structural highlights

2dtt is a 6 chain structure with sequence from Pyrococcus horikoshii OT3. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

O58368_PYRHO

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2dtt, resolution 2.20Å

Drag the structure with the mouse to rotate

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OCA
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