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[[Image:2dsn.jpg|left|200px]]<br /><applet load="2dsn" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2dsn, resolution 1.50&Aring;" />
'''Crystal structure of T1 lipase'''<br />


==About this Structure==
==Crystal structure of T1 lipase==
2DSN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Geobacillus_zalihae Geobacillus zalihae] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=NA:'>NA</scene> and <scene name='pdbligand=CL:'>CL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Triacylglycerol_lipase Triacylglycerol lipase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.3 3.1.1.3] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DSN OCA].  
<StructureSection load='2dsn' size='340' side='right'caption='[[2dsn]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2dsn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_zalihae Geobacillus zalihae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DSN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DSN FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dsn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dsn OCA], [https://pdbe.org/2dsn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dsn RCSB], [https://www.ebi.ac.uk/pdbsum/2dsn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dsn ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q842J9_9BACI Q842J9_9BACI]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ds/2dsn_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dsn ConSurf].
<div style="clear:both"></div>


==Reference==
==See Also==
Novel cation-pi interaction revealed by crystal structure of thermoalkalophilic lipase., Matsumura H, Yamamoto T, Leow TC, Mori T, Salleh AB, Basri M, Inoue T, Kai Y, Rahman RN, Proteins. 2008 Feb 1;70(2):592-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17932933 17932933]
*[[Lipase 3D Structures|Lipase 3D Structures]]
__TOC__
</StructureSection>
[[Category: Geobacillus zalihae]]
[[Category: Geobacillus zalihae]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Triacylglycerol lipase]]
[[Category: Kai Y]]
[[Category: Kai, Y.]]
[[Category: Matsumura H]]
[[Category: Matsumura, H.]]
[[Category: CA]]
[[Category: CL]]
[[Category: NA]]
[[Category: ZN]]
[[Category: hydrolase]]
[[Category: t1 lipase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:02:10 2008''

Latest revision as of 11:29, 25 October 2023

Crystal structure of T1 lipaseCrystal structure of T1 lipase

Structural highlights

2dsn is a 2 chain structure with sequence from Geobacillus zalihae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.5Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q842J9_9BACI

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2dsn, resolution 1.50Å

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