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==Crystal Structure Of Unliganded Form Of Oligomeric E.coli Guanylate Kinase==
==Crystal Structure Of Unliganded Form Of Oligomeric E.coli Guanylate Kinase==
<StructureSection load='2anc' size='340' side='right' caption='[[2anc]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
<StructureSection load='2anc' size='340' side='right'caption='[[2anc]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2anc]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ANC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ANC FirstGlance]. <br>
<table><tr><td colspan='2'>[[2anc]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ANC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ANC FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2an9|2an9]], [[2anb|2anb]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gmk ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2anc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2anc OCA], [https://pdbe.org/2anc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2anc RCSB], [https://www.ebi.ac.uk/pdbsum/2anc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2anc ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Guanylate_kinase Guanylate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.8 2.7.4.8] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2anc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2anc OCA], [http://pdbe.org/2anc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2anc RCSB], [http://www.ebi.ac.uk/pdbsum/2anc PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/KGUA_ECOLI KGUA_ECOLI]] Essential for recycling GMP and indirectly, cGMP.<ref>PMID:8390989</ref>
[https://www.uniprot.org/uniprot/KGUA_ECOLI KGUA_ECOLI] Essential for recycling GMP and indirectly, cGMP.<ref>PMID:8390989</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/an/2anc_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/an/2anc_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
*[[Guanylate kinase|Guanylate kinase]]
*[[Guanylate kinase 3D structures|Guanylate kinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Guanylate kinase]]
[[Category: Large Structures]]
[[Category: Cherfils, J]]
[[Category: Cherfils J]]
[[Category: Christova, P]]
[[Category: Christova P]]
[[Category: Evrin, C]]
[[Category: Evrin C]]
[[Category: Gilles, A M]]
[[Category: Gilles AM]]
[[Category: Hible, G]]
[[Category: Hible G]]
[[Category: Radulescu, A Z]]
[[Category: Radulescu AZ]]
[[Category: Renault, L]]
[[Category: Renault L]]
[[Category: Schaeffer, F]]
[[Category: Schaeffer F]]
[[Category: Gmp kinase]]
[[Category: Oligomeric]]
[[Category: Transferase]]

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