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[[Image:1xc1.gif|left|200px]]


{{Structure
==Oxo Zirconium(IV) Cluster in the Ferric Binding Protein (FBP)==
|PDB= 1xc1 |SIZE=350|CAPTION= <scene name='initialview01'>1xc1</scene>, resolution 1.51&Aring;
<StructureSection load='1xc1' size='340' side='right'caption='[[1xc1]], [[Resolution|resolution]] 1.51&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=ZRC:OXO+ZIRCONIUM(IV)+CLUSTER'>ZRC</scene>
<table><tr><td colspan='2'>[[1xc1]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_gonorrhoeae Neisseria gonorrhoeae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XC1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XC1 FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.51&#8491;</td></tr>
|GENE= FBPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=485 Neisseria gonorrhoeae])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZRC:OXO+ZIRCONIUM(IV)+CLUSTER'>ZRC</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xc1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xc1 OCA], [https://pdbe.org/1xc1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xc1 RCSB], [https://www.ebi.ac.uk/pdbsum/1xc1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xc1 ProSAT]</span></td></tr>
|RELATEDENTRY=[[1o7t|1O7T]], [[1r1n|1R1N]], [[1d91|1D91]]
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xc1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xc1 OCA], [http://www.ebi.ac.uk/pdbsum/1xc1 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1xc1 RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/FBP_NEIGO FBP_NEIGO] This protein may be a central component in the iron-acquisition system.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xc/1xc1_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xc1 ConSurf].
<div style="clear:both"></div>


'''Oxo Zirconium(IV) Cluster in the Ferric Binding Protein (FBP)'''
==See Also==
 
*[[Ferric-binding protein|Ferric-binding protein]]
 
__TOC__
==About this Structure==
</StructureSection>
1XC1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Neisseria_gonorrhoeae Neisseria gonorrhoeae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XC1 OCA].
[[Category: Large Structures]]
 
==Reference==
Assembly of an oxo-zirconium(IV) cluster in a protein cleft., Zhong W, Alexeev D, Harvey I, Guo M, Hunter DJ, Zhu H, Campopiano DJ, Sadler PJ, Angew Chem Int Ed Engl. 2004 Nov 12;43(44):5914-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15472987 15472987]
[[Category: Neisseria gonorrhoeae]]
[[Category: Neisseria gonorrhoeae]]
[[Category: Single protein]]
[[Category: Alexeev D]]
[[Category: Alexeev, D.]]
[[Category: Campopiano DJ]]
[[Category: Campopiano, D J.]]
[[Category: Guo M]]
[[Category: Guo, M.]]
[[Category: Harvey I]]
[[Category: Harvey, I.]]
[[Category: Hunter DJB]]
[[Category: Hunter, D J.B.]]
[[Category: Sadler PJ]]
[[Category: Sadler, P J.]]
[[Category: Zhong W]]
[[Category: Zhong, W.]]
[[Category: Zhu H]]
[[Category: Zhu, H.]]
[[Category: metal-oxo cluster]]
[[Category: periplasmic ferric binding protein]]
[[Category: zirconium]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:47:32 2008''

Latest revision as of 11:06, 25 October 2023

Oxo Zirconium(IV) Cluster in the Ferric Binding Protein (FBP)Oxo Zirconium(IV) Cluster in the Ferric Binding Protein (FBP)

Structural highlights

1xc1 is a 9 chain structure with sequence from Neisseria gonorrhoeae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.51Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

FBP_NEIGO This protein may be a central component in the iron-acquisition system.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1xc1, resolution 1.51Å

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OCA
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