1wsv: Difference between revisions

<StructureSection load='1wsv' size='340' side='right'caption='[[1wsv]], [[Resolution|resolution]] 2.60&Aring;' scene=''>

<table><tr><td colspan='2'>[[1wsv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WSV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WSV FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=THH:N-[4-({[(6S)-2-AMINO-4-HYDROXY-5-METHYL-5,6,7,8-TETRAHYDROPTERIDIN-6-YL]METHYL}AMINO)BENZOYL]-L-GLUTAMIC+ACID'>THH</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wsv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wsv OCA], [https://pdbe.org/1wsv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wsv RCSB], [https://www.ebi.ac.uk/pdbsum/1wsv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wsv ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/GCST_HUMAN GCST_HUMAN] Defects in AMT are a cause of non-ketotic hyperglycinemia (NKH) [MIM:[https://omim.org/entry/605899 605899]; also known as glycine encephalopathy (GCE). NKH is an autosomal recessive disease characterized by accumulation of a large amount of glycine in body fluid and by severe neurological symptoms.<ref>PMID:8005589</ref> <ref>PMID:9600239</ref> <ref>PMID:9621520</ref> <ref>PMID:10873393</ref> <ref>PMID:11286506</ref>  

[https://www.uniprot.org/uniprot/GCST_HUMAN GCST_HUMAN] The glycine cleavage system catalyzes the degradation of glycine.

*[[Aminomethyltransferase 3D structures|Aminomethyltransferase 3D structures]]

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Fujiwara K]]

[[Category: Hosaka H]]

[[Category: Motokawa Y]]

[[Category: Nakagawa A]]

[[Category: Okamura-Ikeda K]]

[[Category: Taniguchi H]]

[[Category: Toma S]]

[[Category: Yamashita E]]

[[Category: Yoshimura M]]