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==Crystal structure of Pyrococcus horikoshii CutA in the presence of 3M guanidine hydrochloride==
==Crystal structure of Pyrococcus horikoshii CutA in the presence of 3M guanidine hydrochloride==
<StructureSection load='1umj' size='340' side='right' caption='[[1umj]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='1umj' size='340' side='right'caption='[[1umj]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1umj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii_ot3 Pyrococcus horikoshii ot3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UMJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UMJ FirstGlance]. <br>
<table><tr><td colspan='2'>[[1umj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UMJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UMJ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GAI:GUANIDINE'>GAI</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1j2v|1j2v]], [[1uku|1uku]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAI:GUANIDINE'>GAI</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PH0992 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=70601 Pyrococcus horikoshii OT3])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1umj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1umj OCA], [https://pdbe.org/1umj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1umj RCSB], [https://www.ebi.ac.uk/pdbsum/1umj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1umj ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1umj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1umj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1umj RCSB], [http://www.ebi.ac.uk/pdbsum/1umj PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CUTA_PYRHO CUTA_PYRHO]] Involved in resistance toward heavy metals.  
[https://www.uniprot.org/uniprot/CUTA_PYRHO CUTA_PYRHO] Involved in resistance toward heavy metals.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/um/1umj_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/um/1umj_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1umj ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 1umj" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[CutA1|CutA1]]
*[[CutA1 3D structures|CutA1 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Pyrococcus horikoshii ot3]]
[[Category: Large Structures]]
[[Category: Kumagai, I]]
[[Category: Pyrococcus horikoshii OT3]]
[[Category: Sakai, N]]
[[Category: Kumagai I]]
[[Category: Tanaka, I]]
[[Category: Sakai N]]
[[Category: Tanaka, Y]]
[[Category: Tanaka I]]
[[Category: Tsumoto, K]]
[[Category: Tanaka Y]]
[[Category: Yao, M]]
[[Category: Tsumoto K]]
[[Category: Yasutake, Y]]
[[Category: Yao M]]
[[Category: Copper tolerance]]
[[Category: Yasutake Y]]
[[Category: Cuta]]
[[Category: Structural genomic]]
[[Category: Unknown function]]

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