1p9b: Difference between revisions
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==Structure of fully ligated Adenylosuccinate synthetase from Plasmodium falciparum== | ==Structure of fully ligated Adenylosuccinate synthetase from Plasmodium falciparum== | ||
<StructureSection load='1p9b' size='340' side='right' caption='[[1p9b]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='1p9b' size='340' side='right'caption='[[1p9b]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1p9b]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1p9b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P9B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P9B FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=HDA:HADACIDIN'>HDA</scene>, <scene name='pdbligand=IMO:6-O-PHOSPHORYL+INOSINE+MONOPHOSPHATE'>IMO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=HDA:HADACIDIN'>HDA</scene>, <scene name='pdbligand=IMO:6-O-PHOSPHORYL+INOSINE+MONOPHOSPHATE'>IMO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p9b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p9b OCA], [https://pdbe.org/1p9b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p9b RCSB], [https://www.ebi.ac.uk/pdbsum/1p9b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p9b ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/PURA_PLAFA PURA_PLAFA] Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).<ref>PMID:12071700</ref> <ref>PMID:15500910</ref> <ref>PMID:20654742</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</div> | </div> | ||
<div class="pdbe-citations 1p9b" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 1p9b" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Adenylosuccinate synthetase 3D structures|Adenylosuccinate synthetase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Plasmodium falciparum]] | ||
[[Category: Anand | [[Category: Anand RP]] | ||
[[Category: Balaram | [[Category: Balaram H]] | ||
[[Category: Eaazhisai | [[Category: Eaazhisai K]] | ||
[[Category: Gayathri | [[Category: Gayathri P]] | ||
[[Category: Jayalakshmi | [[Category: Jayalakshmi R]] | ||
[[Category: Murthy | [[Category: Murthy MR]] | ||
[[Category: Sumathy | [[Category: Sumathy K]] | ||