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[[Image:1ma1.gif|left|200px]]<br /><applet load="1ma1" size="350" color="white" frame="true" align="right" spinBox="true"
caption="1ma1, resolution 2.6&Aring;" />
'''Structure and properties of the atypical iron superoxide dismutase from Methanobacterium thermoautotrophicum'''<br />


==About this Structure==
==Structure and properties of the atypical iron superoxide dismutase from Methanobacterium thermoautotrophicum==
1MA1 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus] with <scene name='pdbligand=FE:'>FE</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MA1 OCA].  
<StructureSection load='1ma1' size='340' side='right'caption='[[1ma1]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1ma1]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MA1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MA1 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ma1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ma1 OCA], [https://pdbe.org/1ma1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ma1 RCSB], [https://www.ebi.ac.uk/pdbsum/1ma1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ma1 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SODF_METTH SODF_METTH] Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ma/1ma1_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ma1 ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Superoxide dismutase 3D structures|Superoxide dismutase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Methanothermobacter thermautotrophicus]]
[[Category: Methanothermobacter thermautotrophicus]]
[[Category: Single protein]]
[[Category: Adams JJ]]
[[Category: Superoxide dismutase]]
[[Category: Anderson BF]]
[[Category: Adams, J J.]]
[[Category: Jameson GB]]
[[Category: Anderson, B F.]]
[[Category: Morgenstern-Badarau I]]
[[Category: Jameson, G B.]]
[[Category: Renault JP]]
[[Category: Morgenstern-Badarau, I.]]
[[Category: Verchere-Beaur C]]
[[Category: Renault, J P.]]
[[Category: Verchere-Beaur, C.]]
[[Category: FE]]
[[Category: azide inhibition]]
[[Category: iron superoxide dismutase]]
[[Category: metal specificity]]
[[Category: peroxide inactivation]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:53:06 2008''

Latest revision as of 10:18, 25 October 2023

Structure and properties of the atypical iron superoxide dismutase from Methanobacterium thermoautotrophicumStructure and properties of the atypical iron superoxide dismutase from Methanobacterium thermoautotrophicum

Structural highlights

1ma1 is a 6 chain structure with sequence from Methanothermobacter thermautotrophicus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.6Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SODF_METTH Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1ma1, resolution 2.60Å

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